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Coccidioidomycosis

Bassem M. Mostafa Elsawy, MD FAAFP AGSF Reviewed 06/2022
 


BASICS

DESCRIPTION

  • A pulmonary fungal infection caused by the dimorphic fungus, Coccidioides immitis, which is endemic to arid areas of the southwestern United States:

    • Transmitted through inhalation of ...

DIAGNOSIS

HISTORY

  • Travel history is essential in pulmonary disease that does not respond to normal treatments.

  • Most humans infected with coccidioidomycosis are asymptomatic or have minimal symptoms (4)...

TREATMENT

GENERAL MEASURES

  • Cool mist humidifier for dry cough or sore throat, antitussives

  • Supportive therapy

  • Most cases resolve without antifungal treatment.

MEDICATION

First Line

  • In mild cases, treatment ...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • If serology is negative but index of suspicion is high, repeat every 2 weeks.

  • With positive serology, follow titers every 2 weeks until are dropp...

REFERENCES

1
Thompson  GRIII. Pulmonary coccidioidomycosis. Semin Respir Crit Care Med.  2011;32(6):754–763. [View Abstract on OvidMedline]
2
...

ADDITIONAL READING

  • Ampel NM. Coccidioidomycosis: changing concepts and knowledge gaps. J Fungi (Basel). 2020;6(4):354.

  • Carey A, Gorris ME, Chiller T, et al. Ep...

CODES

ICD10

  • B38.9 Coccidioidomycosis, unspecified

  • B38.2 Pulmonary coccidioidomycosis, unspecified

  • B38.0 Acute pulmonary coccidioidomycosis

  • B38.1 Chronic pulmonary coccidioidomycosis

  • B38.89 Other forms of c...

CLINICAL PEARLS

  • Consider coccidioidomycosis in patients who have traveled to or live in endemic areas presenting with persistent pulmonary symptoms that do not respond to routine treatment.

  • Even minima...

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