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Coccidioidomycosis

Asma Tariq, M.D, Rebecca R K Kawagoe, M.S., D.O. and Mariam Bassali, M.P.H., M.D. Reviewed 04/2024
 


BASICS

DESCRIPTION

  • A pulmonary fungal infection caused by the dimorphic fungus, Coccidioides, endemic to arid areas of the southwestern United States as well as parts of Central and South America.

    • Trans...

DIAGNOSIS

HISTORY

  • Presentations in symptomatic patients include:

    • Acute pneumonia (most common): cough, fever, chest pain, headache, malaise, arthralgias, skin rash (erythema nodosum or erythema multifor...

TREATMENT

Most coccidioidomycosis infections are asymptomatic or have minimal symptoms. 
  • Approximately 60% of patients are either asymptomatic or develop mild respiratory illness.

  • Expert opinion varies ...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Monitor all patients for complications including relapse regardless of antifungal therapy.

  • Evaluate for clinical, serological, and radiographic i...

REFERENCES

1
Crum NF. Coccidioidomycosis: a contemporary review Infect Dis Ther. 2022;11(2):713–742. doi: 10.1007/s40121-022-00606-y.
2
Bays DJ, Thompson GR 3rd. Coccidioidomycosis. Infect Dis Clin North...

ADDITIONAL READING

Ampel NM. Coccidioidomycosis: changing concepts and knowledge gaps. J Fungi (Basel). 2020;6(4):354.  

CODES

ICD10

  • B38.9 Coccidioidomycosis, unspecified

  • B38.2 Pulmonary coccidioidomycosis, unspecified

  • B38.0 Acute pulmonary coccidioidomycosis

  • B38.1 Chronic pulmonary coccidioidomycosis

  • B38.89 Other forms of c...

CLINICAL PEARLS

  • Consider coccidioidomycosis in patients who have traveled to or live in endemic areas who present with persistent pulmonary symptoms that do not respond to routine treatment. Even mini...

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