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Coccidioidomycosis

Asma Tariq, MD, Rebecca Kawagoe, MS, DO and Stephen C. Zerlang, DO Reviewed 05/2023
 


BASICS

DESCRIPTION

  • A pulmonary fungal infection caused by the dimorphic fungus, Coccidioides, endemic to arid areas of the southwestern United States:

    • Transmitted through inhalation of air-borne fungal ...

DIAGNOSIS

HISTORY

  • Presentations in symptomatic patients include:

    • Acute pneumonia (most common): cough, fever, chest pain, headache, malaise, arthralgias, skin rash (erythema nodosum or erythema multifor...

TREATMENT

  • Most coccidioidomycosis infections are asymptomatic or have minimal symptoms.

    • ~95% of those who develop symptoms have self-limited disease that resolve within several weeks.

  • In mild cases with...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • If serology is negative but index of suspicion is high, repeat every 2 weeks.

  • With positive serology, follow titers every 2 weeks until or negati...

REFERENCES

1
Crum NF. Coccidioidomycosis: a contemporary review Infect Dis Ther. 2022;11(2):713–742. doi: 10.1007/s40121-022-00606-y.
2
Bays DJ, Thompson GR 3rd. Coccidioidomycosis. Infect Dis Clin North...

ADDITIONAL READING

Ampel NM. Coccidioidomycosis: changing concepts and knowledge gaps. J Fungi (Basel). 2020;6(4):354.  

CODES

ICD10

  • B38.9 Coccidioidomycosis, unspecified

  • B38.2 Pulmonary coccidioidomycosis, unspecified

  • B38.0 Acute pulmonary coccidioidomycosis

  • B38.1 Chronic pulmonary coccidioidomycosis

  • B38.89 Other forms of c...

CLINICAL PEARLS

  • Consider coccidioidomycosis in patients who have traveled to or live in endemic areas presenting with persistent pulmonary symptoms that do not respond to routine treatment. Even minim...

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