A chronic, progressive inflammatory GI tract disorder, most commonly involving the terminal ileum (80%)
Hallmark features of Crohn disease (CD)
Transmural inflammation that can result ...
Factors exacerbating C...
Disease activity: Harvey Bradshaw Index or Crohn Disease Activity Index (CDAI)
Disease severity: risk stratification for rapidly progressive disease
Risk factors for high-risk disease: age at ...
Monitor CBC, BMP, LFTs every 3-4 months.
Actively monitor disease with CRP and/or calprotectin every 6 months.
With azathioprine or 6-mercaptopurine therapy, check ...
K50.0 Crohn's disease of small intestine
K50.113 Crohn's disease of large intestine with fistula
K50.011 Crohn's disease of small intestine with rectal bleeding
K50.01 Crohn's disease of small...
Cigarette smoking doubles the risk of CD; tobacco cessation reduces flares and need for surgery.
MRE allows assessment of luminal and extraluminal CD without radiation exposure.
Assess f...
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FIG. 2.62. Crohn disease. <bold>A:</bold> Fat-suppressed T2-weighted image of lower abdomen demonstrates thickening and increased signal intensity of left colon (<italic>arrow</bold>) in patient with active Crohn disease. <bold>B:</bold> Non–fat-suppressed coronal HASTE image of same patient as <bold>(A)</bold> demonstrates colon wall thickening (<italic>arrow</bold>), but lack of fat suppression limits assessment of edema and fluid.
FIG. 2.62. Crohn disease. <bold>A:</bold> Fat-suppressed T2-weighted image of lower abdomen demonstrates thickening and increa...
FIGURE 93.5. Crohn’s disease of the terminal ileum demonstrated by severe narrowing of the terminal ileum (as shown between the two <italic>arrows</bold>). The cecum is represented by the “C.”
FIGURE 93.5. Crohn’s disease of the terminal ileum demonstrated by severe narrowing of the terminal ileum (as shown between the two <it...
<bold>Fig GI 19-6 Crohn's disease.</bold> Severe postbulbar narrowing with distal fold thickening.
<bold>Fig GI 27-14 Crohn's disease.</bold> Multiple polypoid lesions in the distal jejunum and proximal ileum show both smooth and lobulated contours.<sup>31</sup>
<bold>Fig GI 27-14 Crohn's disease.</bold> Multiple polypoid lesions in the distal jejunum and proximal ileum show both smooth...
<bold>FIGURE 39-4</bold> Crohn disease. The mucosal surface of the colon displays a "cobblestone" appearance owing to the presence of linear ulcerations and edema and inflammation of the intervening tissue.
<bold>FIGURE 39-4</bold> Crohn disease. The mucosal surface of the colon displays a "cobblestone" appearance owing to the pres...
<bold>FIGURE 51.1</bold> Mucosal ulcerations (<italic>arrows</bold>) in Crohn disease of the small bowel.
<bold>FIGURE 51.2</bold> Islands of edematous mucosa surrounded by linear ulceration showing the classic "cobblestone" appearance of Crohn disease.
<bold>FIGURE 51.2</bold> Islands of edematous mucosa surrounded by linear ulceration showing the classic "cobblestone" appeara...
<bold>FIGURE 51.3</bold> Severe Crohn disease affecting the terminal ileum (<italic>white arrow</bold>) with normal ileum for comparison (<italic>black arrow</bold>).
<bold>FIGURE 51.3</bold> Severe Crohn disease affecting the terminal ileum (<italic>white arrow</bold>) with norma...
<bold>FIGURE 51.12</bold> Crohn disease of the ileum (<italic>arrow</bold>) as seen laparoscopically.