Cryoglobulins (CGs) consist of immunoglobulins (Igs) and complement precipitating in serum and plasma.
CGs precipitate at cold temperatures 98.6°F (<37°C) and dissolve on rewarming...
More frequent association with signs of peripheral vessel occlusion (e.g., Raynaud phenomenon, acrocyanosis, livedo reticularis, purpura, ulcers, gangrene), less w...
Symptomatic management of vasculitis and/or hyperviscosity and limit damage caused by circulating immune complexes
Limit or suppress B-lymphocyte proliferation.
Eradicate HCV (if applica...
Alpers CE, Smith KD. Cryoglobulinemia and renal disease. Curr Opin Nephrol Hypertens.
2008; 17(3): 243– 249.
30911005 cryoglobulinemia (disorder)
38675009 Monoclonal cryoimmunoglobulinemia (disorder)
44371002 Mixed polyclonal cryoimmunoglobulinemia (disorder)
CGs are circulating Igs that precipitate at cold temperatures (below 37°C) and dissolve on rewarming.
Type I: associated with lymphoproliferative disorders (e.g., multiple myeloma, Wald...
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