Although most cytomegalovirus (CMV) infections are asymptomatic or cause mild disease, dis...
Congenital
~1% (0.2–2.2%) of newborns are congenitally infected with CMV (3).
Most infected newborns appear normal and are asymptomatic, although as many as 7–15% develop sensorineura...
Congenital disease: ganciclovir 6 mg/kg IV q12h for 6 weeks (3)[A], alternately valganciclovir 16 mg/kg PO q12h for 6 weeks if patient is >7 days old and can tolerate ...
CMV urine culture at birth for all HIV-infected or exposed with annual testing in CMV seronegative/HIV+ children
Patients with CD4 counts <50 ...
Lollinga WT, Rurenga-Gard L, van Doesum W, et al. High human cytomegalovirus DNAemia early post-transplantation associates with irreversible and progressive loss of renal function—a...
B25.9 Cytomegaloviral disease, unspecified
P35.1 Congenital cytomegalovirus infection
B25.8 Other cytomegaloviral diseases
078.5 Cytomegaloviral disease
771.1 Congenital cytomegalovirus inf...
CMV is a major cause of sensorineural hearing loss in young children.
CMV exposure is ubiquitous; up to 97% of adults have antibodies to CMV.
CMV mononucleosis syndrome has less cervical...
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<bold>FIGURE 42-2</bold> <bold>Clinical appearance and radiologic findings of infants with congenital cytomegalovirus. A.</bold> Infant with severe congenital CMV with stigmata of disease, including petechial rash, microcephaly, jaundice, and abnormal posture of upper extremities secondary to central nervous system (CNS) damage. <bold>B.</bold> Computerized tomographic image of an infant with CNS damage secondary to congenital CMV with severe periventricular calcificatio...
<bold>FIGURE 42-2</bold> <bold>Clinical appearance and radiologic findings of infants with congenital cytomegalovirus. ...
FIGURE 58.1. A: Lung tissue with characteristic "owl's-eye" cytomegalovirus nuclear inclusion and cytoplasmic inclusions (H&E, 31,000, oil). B: Esophageal tissue with herpes virus intranuclear inclusions with multinucleation (H&E, 31,000, oil). C: Lung tissue with a "smudged" intranuclear inclusion characteristic of adenovirus (center H&E, 31,000, oil). D: Heart tissue with an intramyocardial Toxoplasma cyst (H3E, 31,000, oil).(continued)
FIGURE 58.1. A: Lung tissue with characteristic "owl's-eye" cytomegalovirus nuclear inclusion and cytoplasmic inclusions (H&E, 31,...
An infant with congenital cytomegalovirus infection. Infant had jaundice, hepatosplenomegaly, and petechiae.
Congenital CMV "blueberry muffin" baby with jaundice and thrombocytopenia purpura.