Ubiquitous and common infection impacting all ages, ethnic, socioeconomic groups, and geographic areas
Although most cytomegalovirus (CMV) infections are asymptomatic or cause mild dis...
Congenital
Most infected newborns appear normal and are asymptomatic, although as many as 7–15% develop sensorineural hearing loss, which can be progressive and have a delayed onset (...
Symptomatic congenital disease: ganciclovir 6 mg/kg IV q12h for 6 weeks (switch to PO valganciclovir when can tolerate) (2)[B],(3)[B], alternatively valganciclovir 16 mg...
CMV antibody testing at age 1, then annually for CMV-seronegative, HIV infected infants/children who are immunosuppressed (3)
Patients on therap...
B25.9 Cytomegaloviral disease, unspecified
P35.1 Congenital cytomegalovirus infection
B25.8 Other cytomegaloviral diseases
28944009 Cytomegalovirus infection (disorder)
59527008 Congenita...
CMV is a major cause of sensorineural hearing loss in young children.
CMV exposure is ubiquitous; up to 97% of adults have antibodies to CMV.
CMV mononucleosis syndrome has less cervical...
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<bold>FIGURE 42-2</bold> <bold>Clinical appearance and radiologic findings of infants with congenital cytomegalovirus. A.</bold> Infant with severe congenital CMV with stigmata of disease, including petechial rash, microcephaly, jaundice, and abnormal posture of upper extremities secondary to central nervous system (CNS) damage. <bold>B.</bold> Computerized tomographic image of an infant with CNS damage secondary to congenital CMV with severe periventricular calcificatio...
<bold>FIGURE 42-2</bold> <bold>Clinical appearance and radiologic findings of infants with congenital cytomegalovirus. ...
FIGURE 58.1. A: Lung tissue with characteristic "owl's-eye" cytomegalovirus nuclear inclusion and cytoplasmic inclusions (H&E, 31,000, oil). B: Esophageal tissue with herpes virus intranuclear inclusions with multinucleation (H&E, 31,000, oil). C: Lung tissue with a "smudged" intranuclear inclusion characteristic of adenovirus (center H&E, 31,000, oil). D: Heart tissue with an intramyocardial Toxoplasma cyst (H3E, 31,000, oil).(continued)
FIGURE 58.1. A: Lung tissue with characteristic "owl's-eye" cytomegalovirus nuclear inclusion and cytoplasmic inclusions (H&E, 31,...
An infant with congenital cytomegalovirus infection. Infant had jaundice, hepatosplenomegaly, and petechiae.
Congenital CMV "blueberry muffin" baby with jaundice and thrombocytopenia purpura.