Dengue Fever

Sean C. Conley, D.O. Reviewed 05/2023

BASICS

DESCRIPTION

ALERT

Dengue fever, or “break-bone fever,” is caused by dengue virus (DENV), an enveloped, positive-sense, single-stranded RNA virus of the Flaviviridae family (1,2,3).
Dengue virus i...

DIAGNOSIS

HISTORY

Dengue fever presents with (3,4):
- High fevers
- Rash
- Headache, retroorbital pain
- Myalgias, arthralgias
- Nausea, vomiting
Severe dengue, in addition to the above, presents with (...

TREATMENT

GENERAL MEASURES

In general, patients diagnosed with dengue fever should be instructed to rest and stay well hydrated. Furthermore, they should be advised to avoid further mosquito exposure t...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

After recovery, dengue patients meeting criteria should be vaccinated to reduce the risk of severe dengue if subsequently infected with a different serotype (4)....

REFERENCES

Bhatt P, Sabeena SP, Varma, M, et al. Current understanding of the pathogenesis of dengue virus infection. Curr Microbiol. 2020;78(1):17–32. doi:10.1007/s00284-020-02284-w

Roy SK, Bhattach...

ADDITIONAL READING

Centers for Disease Control and Prevention. Dengue cheat sheet. 2015. Retrieved October 30, 2022. https://www.cdc.gov/dengue/resources/DengueCheatSheet_ENG-P.pdf. ...

CODES

ICD10

A90 Dengue fever [classical dengue]
A91 Dengue hemorrhagic fever

SNOMED

38362002 Dengue (disorder)
20927009 Dengue hemorrhagic fever (disorder)

CLINICAL PEARLS

Appropriately identifying the stage of disease is paramount to providing prompt and adequate therapy, especially for those with DHS and DSS (4).
Hemoconcentration may indicate the need...

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