Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) depressive disorders include major depressive disorder (MDD), disruptive mood dysregulation disorder (DMDD)...
Adolescents may present with medically unexplained somatic complaints (fatigue, irritability, headache).
Based on DSM-5 criteria, ≥5 of the following symptoms have been present during ...
Active support and monitoring with short validated scales should be used in mild cases for 6 to 8 weeks.
Psychotherapy and/or medication should be considered if active support...
SSRI medications include black box warning to monitor for worsening condition, behavior changes, and suicidal thoughts (6)[A]
Systematic and regu...
F32.9 Major depressive disorder, single episode, unspecified
F33.9 Major depressive disorder, recurrent, unspecified
F32.8 Other recurrent depressive disorders
F32.8 Other depressive episodes
Adolescent depression is underdiagnosed and often presents with irritability and anhedonia.
Fluoxetine is the most studied FDA-approved treatment for adolescent depression.
Escitalopram,...
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Antidepressant drugs and the biochemical life cycles of norepinephrine and serotonin. MAO inhibitors, tricyclics, and SSRIs are used as antidepressants. MAO inhibitors enhance the actions of NE and 5-HT by preventing their enzymatic destruction. Tricyclics enhance NE and 5-HT action by blocking uptake. SSRIs act the same way but are selective for serotonin.
Antidepressant drugs and the biochemical life cycles of norepinephrine and serotonin. MAO inhibitors, tricyclics, and SSRIs are used as ant...