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Depression

Afsha Rais Kaisani, FAAFP, MD, Tasaduq Hussain Mir, FAAFP, MD and Michael A Armstrong, MD Reviewed 04/2024
 


BASICS

DESCRIPTION

Primary mood disorder characterized by a sustained feeling of sadness and/or decreased interest in all or most activities once enjoyed, which represents a change from previous state....

DIAGNOSIS

DSM-5 requires the following criteria for MDD: 
  • Criterion A: ≥5 of the following symptoms present nearly every day during the same 2-week period, with at least 1 being either depressed mood o...

TREATMENT

American Psychiatric Association (APA) treatment guideline recommend the following: 
  • Acute phase (first 3 months of treatment)

    • Full evaluation, including risk to self and others, wit...

ONGOING CARE

PATIENT EDUCATION

  • Medications may take 2-4 weeks before beneficial effect is noted. Recommend exercise, good sleep hygiene, nutrition and avoid tobacco and alcohol use.

  • The National Suicide...

REFERENCE

1
Hasin DS, Sarvet AL, Meyers JL, et al. Epidemiology of Adult DSM-5 Major Depressive Disorder and Its Specifiers in the United States. JAMA Psychiatry. 2018;75(4):336-346. doi: 10.1001/jamap...

SEE ALSO

Depression, Geriatric; Depression, Pediatric; Depression, Postpartum; Depression, Treatment Resistant; Suicide; Suicide, Pediatric 

CODES

ICD10

  • F32.9 Major depressive disorder, single episode, unspecified

  • F33.9 Major depressive disorder, recurrent, unspecified

  • F34.1 Dysthymic disorder

  • F32.8 Other depressive episodes

  • F33.8 Other recurre...

CLINICAL PEARLS

  • Pharmacotherapy and psychotherapy, alone, can relieve depressive symptoms, however, combination therapy has high rates of improvement.

  • Provide close follow up and education for monitori...

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