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Depression

Reviewed 06/2022
 


BASICS

DESCRIPTION

A primary mood disorder characterized by a sustained feeling of sadness and/or decreased interest in all or most activities once enjoyed (anhedonia), which represents a change from p...

DIAGNOSIS

DSM-5 requires the following criteria for MDD: 
  • Criterion A: ≥5 of the following symptoms present nearly every day during the same 2-week period, with at least 1 of the 5 being either depress...

TREATMENT

American Psychiatric Association (APA) 2010 treatment guideline recommend the following  (1)[C]: 
  • Acute phase (first 3 months of treatment)

    • Full evaluation, including risk to self an...

ONGOING CARE

PATIENT EDUCATION

  • Depression is a common, treatable medical illness and not a character defect.

  • Medications may need to be taken for at least 2 to 4 weeks before any beneficial effect is no...

REFERENCE

1
American Psychiatric Association. Practice guideline for the treatment of patients with major depressive disorder. 2010.  https://psychiatryonline.org/pb/assets/raw/sitewide/practice_guidel...

SEE ALSO

  • Depression, Geriatric; Depression, Pediatric; Depression, Postpartum; Depression, Treatment Resistant; Suicide; Suicide, Pediatric

CODES

ICD10

  • F32.9 Major depressive disorder, single episode, unspecified

  • F33.9 Major depressive disorder, recurrent, unspecified

  • F34.1 Dysthymic disorder

  • F32.8 Other depressive episodes

  • F33.8 Other recurre...

CLINICAL PEARLS

  • Therapeutic alliance is important to treatment success.

  • Given the high recurrence rates, long-term treatment is often necessary.

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