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Dermatitis, Exfoliative

Alvaro J. Ramos-Rodriguez, MD, Dmitriy Timerman, MD and Rafael F. Martin, MD Reviewed 06/2019
 


BASICS

  • Exfoliative dermatitis (ED), also known as erythroderma, is a rare and severe cutaneous disorder characterized by generalized erythema involving >90% of the skin and variable degree of scali...

DIAGNOSIS

  • Diagnosis is made on a clinical basis.

  • Determination of the cause is often elusive, but history is the most important aid in finding the underlying etiology of ED.

  • A skin biopsy can reveal fea...

TREATMENT

  • Wet dressings

  • Intermediate-strength topical steroids (e.g., triamcinolone cream 0.025–0.1%) beneath wet dressings

  • Colloid oatmeal baths

  • Local bland moisturizing ointment

  • Systemic antibiotics if ...

ONGOING CARE

DIET

  • Increase fluid intake.

  • Ensure adequate nutrition with emphasis on sufficient protein intake.

PROGNOSIS

  • Depending on the underlying cause and possible complications, overall mortality may...

REFERENCES

1
Li J, Zheng HY. Erythroderma: a clinical and prognostic study. Dermatology.  2012;225(2):154–162. [View Abstract on OvidMedline]
2
Miyagaki T, Sugaya M. Erythrodermic cutaneous T-cell l...

ADDITIONAL READING

  • Okoduwa C, Lambert WC, Schwartz RA, et al. Erythroderma: review of a potentially life-threatening dermatosis. Indian J Dermatol.  2009;54(1):1–6. [View Abstract on OvidMedline]

  • ...

SEE ALSO

Algorithm: Rash 

CODES

ICD10

  • L26 Exfoliative dermatitis

  • L53.9 Erythematous condition, unspecified

  • L27.0 Gen skin eruption due to drugs and meds taken internally

ICD9

  • 695.89 Other specified erythematous conditions

  • 695.9 Unsp...

CLINICAL PEARLS

  • In its more severe manifestations, ED is a medical and dermatologic emergency.

  • In many cases, the underlying cause may be elusive or never found.

  • Prednisone is generally contraindicated ...

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