Skip to main content

Diabetes Insipidus

Asma Tariq and Lilly M. Varner, M.D. Reviewed 06/2022
 


BASICS

DESCRIPTION

  • A condition in which there is reduced ability to concentrate the urine due to impaired reabsorption of water in the renal collecting tubules.

  • It is characterized by polyuria and, in s...

DIAGNOSIS

Can be challenging, given the variety of causes and variable symptomatology 
  • DI not resulting from a recognizable, acute event (e.g., head trauma) tends to be indolent and, if water needs are...

TREATMENT

GENERAL MEASURES

  • Control fluid balance; prevent dehydration.

  • Check weight daily.

  • Careful follow-up and management of electrolytes.

  • NDI: Correct hypercalcemia and hypokalemia, and discontinue cau...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Regular follow-up at 2- to 3-week intervals initially and 3 to 4 months later

  • Adjust treatment on the basis of urine and electrolyte concentratio...

REFERENCES

1
Aleksandrov  N, Audibert  F, Bedard  MJ, et al. Gestational diabetes insipidus: a review of an underdiagnosed condition. J Obstet Gynaecol Can. ...

CODES

ICD10

  • E23.2 Diabetes insipidus

  • N25.1 Nephrogenic diabetes insipidus

SNOMED

  • 15771004 Diabetes insipidus (disorder)

  • 111395007 Nephrogenic diabetes insipidus (disorder)

  • 45369008 Neurohypophyseal diabetes...

CLINICAL PEARLS

  • Suspect DI in any individual who has polyuria (urine volume > 3 L/day ) and produces hypotonic urine.

  • Water deprivation test and measurement of plasma ADH levels (if available) help ...

Subscribe to Access Full Content

Sign Up for a 10-Day Free Trial

Sign up for a 10-day FREE Trial now and receive full access to all content.

×