Type 1 diabetes mellitus (T1DM) is a chronic disease caused by insulin deficiency following β-cell destruction.
Results in hyperglycemia and potential end-organ complications.
Features...
New-onset polyuria and polydipsia.
Polyuria may present as nocturia, bed-wetting, or incontinence in a previously continent child.
Polyuria may be difficult to appreciate in diaper-clad...
Insulin is the mainstay of therapy.
Education regarding matching of mealtime insulin dose to carbohydrate intake, premeal blood glucose level, and anticipated activity
Premeal ...
To reduce hypoglycemia, patients should lower basal requirements (temporary basal rate if using an insul...
E10.9 Type 1 diabetes mellitus without complications
E10.8 Type 1 diabetes mellitus with unspecified complications
E10.69 Type 1 diabetes mellitus with other specified complication
E10.29 Type...
The age of presentation of T1DM is bimodal: one peak at 4 to 6 years of age and a second peak at 10 to 14 years of age.
At least one autoantibody is present in 85–90% of individuals whe...
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Homeless diabetic man with painful foot showing gangrene and dystrophic nails
<bold><italic>Figure 14.60.</bold></bold> Pretibial diabetic skin changes: necrobiosis lipoidica diabeticorum.
FIG. 11 Diabetic patient with acute spontaneous onset of low back pain and fever. <bold>A,B:</bold> Dramatic elements of two-level spondylodiscitis, L3-5, with secondary communicating psoas abscess component.
FIG. 11 Diabetic patient with acute spontaneous onset of low back pain and fever. <bold>A,B:</bold> Dramatic elements of two-l...
<bold>Figure 11.93. Neuropathic (Charcot) joints in two diabetic patients. A.</bold> Radiographs of both feet show bilateral neuropathic joints at the first metatarsophalangeal joints (<italic>arrows</bold>). On the left there is periarticular osteopenia, indicating superimposed infection. Frontal <bold>(B)</bold> and lateral <bold>(C)</bold> knee radiographs of another patient show disintegration of the knee joint with considerable bony debris (" bag of bones") and a large joint effusion. In the past, involvement o...
<bold>Figure 11.93. Neuropathic (Charcot) joints in two diabetic patients. A.</bold> Radiographs of both feet show bilateral n...
Necrobiosis lipoidica diabeticorum. Atrophic patch present x 6 mo.