Diabetic Polyneuropathy

Symmetric polyneuropathy

• Distal sensory or sensorimotor

Mononeuropathy, radiculopathy, and polyradiculopath...

Most common form (typical): symmetric distal sensory or sensorimotor polyneuropathy

• Distressing numbness, tingling, pain of legs/feet, usually worse at night; allodynia; hyperalgesia

• ...

Maintain blood glucose close to normal.

Provide appropriate footwear to prevent pressure damage to insensate feet.

Generalized symmetric polyneuropathies

• Usually slow, chronic progression

• Insensitive but painless foot as pain lessens

Focal neuropathies

• Recovery over months to years

Cooper TE, Chen J, Wiffen PJet al. Morphine for chronic neuropathic pain in adults. Cochrane Database Syst Rev.  2017;5(5):CD011669. [View Abstract on OvidMedline]

Finnerup NB, ...

E10.42 Type 1 diabetes mellitus with diabetic polyneuropathy

E11.42 Type 2 diabetes mellitus with diabetic polyneuropathy

E13.42 Oth diabetes mellitus with diabetic polyneuropathy

E08.42 Diabe...

Occasionally, when glycemic control improves dramatically, as can occur when treatment for diabetes is initiated, there may be a worsening of neuropathy symptoms (described as treatmen...