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Ductal Carcinoma In Situ

Anne Campbell Larkin, MD Reviewed 04/2024
 


BASICS

DESCRIPTION

  • Ductal carcinoma in situ (DCIS) is a heterogeneous group of premalignant lesions that have the presence of neoplasticclonal proliferation of noninvasive epithelial cells confined to...

DIAGNOSIS

PHYSICAL EXAM

  • CBE with patient in upright and supine position; evaluating for asymmetry, spontaneous discharge, skin changes (peau d’orange, erythema, scaling); nipple retraction/excoriation ...

TREATMENT

MEDICATION

  • Secondary chemoprevention following breast-conserving surgery for ER+ DCIS:

    • Tamoxifen for pre-menopausal patients or tamoxifen or an aromatase inhibitor for post-menopa...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • History and physical exam should occur every 6 to 12 months for the first 5 years and then annually after that.

  • Mammography every 12 months (first mammogram 6 to 1...

REFERENCES

1
American Cancer Society. Cancer Statistics Center. http://cancerstatisticscenter.cancer.org. Accessed May 14, 2023.

SEE ALSO

Breast Cancer 

CODES

ICD10

  • D05.10 Intraductal carcinoma in situ of unspecified breast

  • D05.11 Intraductal carcinoma in situ of right breast

  • D05.12 Intraductal carcinoma in situ of left breast

  • R92.0 Mammographic microcalc...

CLINICAL PEARLS

  • DCIS is a heterogeneous group of noninvasive neoplastic breast ductal epithelial cell lesions.

  • The incidence of DCIS has continued to increase in women with increase in age;more stable ...

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