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Dyspepsia, Functional

Tya-Mae Y Julien, M.D. Reviewed 04/2024
 


BASICS

DESCRIPTION

  • The presence of bothersome postprandial fullness, early satiety, or epigastric pain/burning in the absence of causative structural disease (to include normal upper endoscopy) for at ...

DIAGNOSIS

HISTORY

  • Postprandial fullness

  • Early satiety

  • Epigastric pain

  • Epigastric burning

  • Symptoms for 3 months

  • Alarm features include (1,2):

    • Unintended weight loss

    • Progressive dysphagia

    • Odynophagia

    • Persistent ...

TREATMENT

GENERAL MEASURES

  • Reassurance/physician support is helpful (1)[C].

  • Treatment is based on presumed etiologies.

  • Discontinue offending medications (1)[C].

  • Routine endoscopy not recommended in dysp...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Provide ongoing support and reassurance.

  • Consider upper endoscopy if persistent symptoms

  • Change medications if no difference in symptoms after 4 w...

REFERENCES

1
Lacy BE, Cangemi DJ. Updates in functional dyspepsia and bloating. Curr Opin Gastroenterol. 2022;38(6):613-619. doi: 10.1097/MOG.0000000000000882. PMID: 36219129.
2
Mo...

ADDITIONAL READING

  • Jones MP, Guthrie-Lyons L, Sato YA, et al. Factors Associated With Placebo Treatment Response in Functional Dyspepsia Clinical Trials. Am J Gastroenterol. ...

SEE ALSO

  • Irritable Bowel Syndrome

  • Algorithm: Dyspepsia

CODES

ICD10

K30 Functional dyspepsia 

SNOMED

3696007 Nonulcer dyspepsia (disorder) 

CLINICAL PEARLS

  • Dyspepsia without underlying organic disease is classified as functional or idiopathic.

  • Consider empiric acid suppression therapy as first line for functional dyspepsia.

  • Extensive diagno...

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