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Dyspepsia, Functional

Kristina G Burgers, MD Reviewed 05/2023
 


BASICS

DESCRIPTION

  • The presence of bothersome postprandial fullness, early satiety, or epigastric pain/burning in the absence of causative structural disease (to include normal upper endoscopy) for at ...

DIAGNOSIS

HISTORY

  • Postprandial fullness (2)

  • Early satiety (2)

  • Epigastric pain (2)

  • Epigastric burning (2)

  • Symptoms for 3 months (2)

  • Alarm features include (3,4,5):

    • Unintended weight loss

    • Progressive dysp...

TREATMENT

GENERAL MEASURES

  • Reassurance/physician support is helpful (3,4)[C].

  • Treatment is based on presumed etiologies.

  • Discontinue offending medications (4)[C].

  • Routine endoscopy not recommended in dy...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Provide ongoing support and reassurance.

  • Consider upper endoscopy if persistent symptoms

  • Change medications if no difference in symptoms after 4 w...

REFERENCES

1
Ford AC, Mahadeva S, Carbone MF, et al. Functional dyspepsia. Lancet. 2020;396(10263):1689-1702. doi: 10.1016/S0140-6736(20)30469-4.
2
Stanghellini  V, Chan  FK, Hasle...

ADDITIONAL READING

  • Garcia-Etxebarria K, Carbone F, Teder-Laving M, et al. A survey of functional dyspepsia in 361,360 individuals: Phenotypic and genetic cross-disease analyses. Neurogastro...

SEE ALSO

  • Irritable Bowel Syndrome

  • Algorithm: Dyspepsia

CODES

ICD10

K30 Functional dyspepsia 

SNOMED

3696007 Nonulcer dyspepsia (disorder) 

CLINICAL PEARLS

  • Dyspepsia without underlying organic disease is classified as being functional or idiopathic.

  • Consider empiric acid suppression therapy as first line for functional dyspepsia.

  • Extensive ...

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