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Endocarditis, Infective

Theodore B. Flaum, DO and Kaitlin Unser, DO Reviewed 04/2024
 


BASICS

Infective endocarditis (IE) is an infection of the inner layer of the heart including the valves (native/prosthetic), interventricular septum, intracardiac devices, chordae tendineae, and mural...

DIAGNOSIS

  • Modified Duke Criteria (clinical criteria for IE (1): 2 major criteria, or 1 major and 3 minor criteria, or 5 minor criteria; possible IE: 1 major and 1 minor or 3 minor criteria; rejected ...

TREATMENT

GENERAL MEASURES

In general, antibiotic therapy for IE should be targeted to the organism isolated from blood cultures. The duration of therapy should be calculated from the first day of the ...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Baseline ECG; monitor ECG for conduction disturbances/MI in initial weeks of therapy.

  • TTE at the conclusion of therapy

  • Blood cultures q48h until n...

REFERENCES

1
McDonald EG, Aggrey G, Aslan AT, et al. Guidelines for Diagnosis and Management of Infective Endocarditis in Adults: A WikiGuidelines Group Consensus Statement. JAMA Netw Open. 2023;6(7):e...

ADDITIONAL READING

SEE ALSO

  • Cimmino G, Bottino R, Formisano T, et al. Current Views on Infective Endocarditis: Changing Epidemiology, Improving Diagnostic Tools and Centering the Patient ...

CODES

ICD10

  • I33.0 Acute and subacute infective endocarditis

  • I39 Endocarditis and heart valve disord in dis classd elswhr

  • A54.83 Gonococcal heart infection

  • B37.6 Candidal endocarditis

SNOMED

  • 233850007 infect...

CLINICAL PEARLS

  • Preprocedural antibiotic prophylaxis is recommended for patients with artificial heart valves, a previous history of IE, CHD, and cardiac transplants with valvulopathy.

  • TEE/TTE and bloo...

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