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Eosinophilic Esophagitis

Shahrad Hakimian, MD Reviewed 06/2022
 


BASICS

DESCRIPTION

  • A chronic, local, immune-mediated, esophageal disease characterized clinically in adults by dysphagia, food impaction, and heartburn and in children with nonspecific abdominal compla...

DIAGNOSIS

There are no pathognomonic findings for EoE. Diagnosis is made by esophageal endoscopy and biopsy, defined as >15 eosinophils/high-powered field on esophageal biopsies of both distal and ...

TREATMENT

End points of therapy for EoE include improvements in clinical symptoms and reducing esophageal eosinophilic inflammation (1)[A]. 

GENERAL MEASURES

Treatment is a combination of dietary chang...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • EoE is a chronic disease with symptoms commonly recurring with nonadherence to dietary or medical interventions. Although not yet standard therapy, consider maint...

REFERENCES

1
Dellon  ES, Gonsalves  N, Hirano  I, et al. ACG clinical guideline: evidenced based approach to the diagnosis and management of esophageal eosinophilia and eosinoph...

ADDITIONAL READING

  • Dellon  ES, Jensen  ET, Martin  CF, et al. Prevalence of eosinophilic esophagitis in the United States. Clin Gastroenterol Hepatol.  2014;12(4):589–5...

CODES

ICD10

K20.0 Eosinophilic esophagitis 

SNOMED

235599003 eosinophilic esophagitis (disorder) 

CLINICAL PEARLS

  • Consider EoE, particularly when young, male patients present with symptoms of food impaction or recurrent solid food dysphagia.

  • EoE mimics GERD. Endoscopic biopsy is required for the di...

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