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Eosinophilic Esophagitis

Shahrad Hakimian, MD Reviewed 04/2024
 


BASICS

DESCRIPTION

  • A chronic, local, immune-mediated, esophageal disease characterized clinically in adults by dysphagia, food impaction, and heartburn and in children with nonspecific abdominal compla...

DIAGNOSIS

There are no pathognomonic findings for EoE. Diagnosis is made by esophageal endoscopy and biopsy, defined as >15 eosinophils/high-powered field on esophageal biopsies of both distal and ...

TREATMENT

End points of therapy for EoE include improvements in clinical symptoms and reducing esophageal eosinophilic inflammation (1). 

GENERAL MEASURES

Treatment is a combination of dietary changes ...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • Serial endoscopy and repeat biopsy in the reintroduction phase of EOE dietary modification has been suggested to more accurately identify etiologic trigger food i...

REFERENCES

1
Muir A, Falk GW. Eosinophilic esophagitis: a review. JAMA. 2021;326(13):1310–1318. doi: 10.1001/jama.2021.14920.
2
Lehman KH, Lam W. Eosinophilic Esophagitis. Immunol Allergy Clin North Am. ...

CODES

ICD10

K20.0 Eosinophilic esophagitis 

SNOMED

235599003 eosinophilic esophagitis (disorder) 

CLINICAL PEARLS

  • Consider EoE, particularly when young, male patients present with symptoms of food impaction or recurrent solid food dysphagia.

  • EoE mimics GERD. Endoscopic biopsy is required for the di...

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