Eosinophilic Esophagitis

Salmaan A. Jawaid, MD, Peter I. Chung, MD and Benjamin Hyatt, MD Reviewed 06/2018

BASICS

A chronic, immune-mediated, inflammatory esophageal disease characterized clinically in adults by dysphagia, food impaction, and heartburn and in children with nonspecific abdominal complaints,...

DIAGNOSIS

There are no pathognomonic findings for EoE. Diagnosis is made by esophageal endoscopy and biopsy.

HISTORY

Solid food dysphagia and food impaction are the most common symptoms and are usually...

TREATMENT

End points of therapy of EoE include improvements in clinical symptoms and reducing esophageal eosinophilic inflammation. Defining evidence-based end points in EoE is an area of active resea...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

EoE is a chronic disease with symptoms commonly recurring after discontinuing dietary or medical interventions. Although not yet standard therapy, consider mainte...

REFERENCES

Dellon ES, Gonsalves N, Hirano I, et al. ACG clinical guidelines: evidenced based approach to diagnosis and management of esophageal eosinophilia and eosinophilic esophagitis (EoE). Am J G...

ADDITIONAL READING

Bohm ME, Richter JE. Review article: oesophageal dilation in adults with eosinophilic oesophagitis. Aliment Pharmacol Ther. 2011;33(7):748–757.
Dellon ES, Jensen ET, Martin CF,...

CODES

ICD10

K20.0 Eosinophilic esophagitis

ICD9

530.13 Eosinophilic esophagitis

SNOMED

235599003 eosinophilic esophagitis (disorder)

CLINICAL PEARLS

Consider EoE, particularly with food impaction or recurrent solid food dysphagia in young, adult males.
EoE commonly mimics GERD and PPI-REE.
A PPI trial is required prior to the diagnos...

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