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Eosinophilic Pneumonias

Spencer Deleveaux, MD and Xavier Fonseca Fuentes, MD Reviewed 06/2022
 


BASICS

DESCRIPTION

  • Eosinophilic pneumonias (pulmonary eosinophilia) represent a rare group of heterogeneous diffuse parenchymal lung diseases, which are characterized by accumulations of infiltrating e...

DIAGNOSIS

  • Symptoms range from mild and insidious to acute and life-threatening; requires a strong index of suspicion

  • AEP:

    • Abrupt onset of fever, usually <5–7 days to <1 month in duration

    • Hypoxemia ...

TREATMENT

Condition can either progress to respiratory failure or resolve spontaneously. 

GENERAL MEASURES

  • Milder cases can be managed as an outpatient; more severe cases require inpatient care.

  • Evaluate...

ONGOING CARE

Can consider switching to inhaled steroids for maintenance treatment in CEP. 

FOLLOW-UP RECOMMENDATIONS

CEP is associated with long term PFT impairment. Follow-up with Pulmonology will assi...

REFERENCES

1
Fernández Pérez  ER, Olson  AL, Frankel  SK. Eosinophilic lung diseases. Med Clin North Am.  2011;95(6):1163–1187. [View Abstract on OvidMedline] ...

ADDITIONAL READING

  • Bartal C, Sagy I, Barski L. Drug-induced eosinophilic pneumonia: a review of 196 case reports. Medicine (Baltimore). 2018;97(4):e9688.

  • Crowe...

SEE ALSO

Aspergillosis; Roundworms, Tissue; Tuberculosis; Wegener Granulomatosis 

CODES

ICD10

J82 Pulmonary eosinophilia, not elsewhere classified 

SNOMED

  • 367542003 Pulmonary eosinophilia (disorder)

  • 64936001 lffler’s syndrome (disorder)

  • 233691007 Asthmatic pulmonary eosinophilia (disord...

CLINICAL PEARLS

  • Eosinophilic pneumonias are rare.

  • Classified as either primary or secondary, acute or chronic

  • Bronchoscopy with bronchoalveolar lavage aids diagnosis.

  • Corticosteroid therapy is effective.

  • ...

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