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Eosinophilic Pneumonias

Alexandria Clarke Kregor, D.O. and Sarah Usmani, MD Reviewed 05/2023
 


BASICS

DESCRIPTION

Eosinophilic pneumonias (pulmonary eosinophilia) are rare heterogeneous diffuse parenchymal lung diseases, characterized by accumulations of infiltrating eosinophils in the alveolar ...

DIAGNOSIS

  • Symptoms range from mild and insidious to acute and life-threatening; requires a strong index of suspicion

  • AEP (2):

    • Acute febrile illness <1 month in duration

    • Hypoxemia (PaO2 <60 mmHg on...

TREATMENT

GENERAL MEASURES

  • Milder cases can be managed as an outpatient; more severe cases require inpatient care.

  • Evaluate for secondary causes.

  • Pulmonary hygiene for secretion clearance

  • Discontinue any ...

ONGOING CARE

Consider switching to inhaled steroids for maintenance treatment in CEP. 

FOLLOW-UP RECOMMENDATIONS

CEP is associated with long-term PFT impairment. Follow-up with Pulmonology will assist w...

REFERENCES

1
Groh  M, Pagnoux  C, Baldini  C, et al. Eosinophilic granulomatosis with polyangiitis (Churg-Strauss) (EGPA) Consensus Task Force recommendations for evaluation and...

ADDITIONAL READING

  • Crowe M, Robinson D, Sagar M, et al. Chronic eosinophilic pneumonia: clinical perspectives. Ther Clin Risk Manag. 2019;15:397–403. 

  • De Giaco...

SEE ALSO

Aspergillosis; Roundworms, Tissue; Tuberculosis; Wegener Granulomatosis 

CODES

ICD10

J82 Pulmonary eosinophilia, not elsewhere classified 

SNOMED

  • 367542003 Pulmonary eosinophilia (disorder)

  • 64936001 lffler’s syndrome (disorder)

  • 233691007 Asthmatic pulmonary eosinophilia (disord...

CLINICAL PEARLS

  • Eosinophilic pneumonias are rare.

  • Classified as either primary or secondary, systemic or lung limited

  • Bronchoscopy with bronchoalveolar lavage aids diagnosis.

  • Corticosteroid therapy is ef...

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