A spectrum of fatty liver diseases not due to excess alcohol consumption ranging from nonalcoholic fatty liver (NAFL), to nonalcoholic steatohepatitis (NASH), to cirrhosis with hepatocyte injur...
Routine screening not recommended
Consider NAFLD in patients with asymptomatic aminotransferase elevations (1)[A].
Can occur with normal AST/ALT levels (1)[A]
NAFLD has no distinguishing histor...
Sustained weight loss (3–5% body weight) through lifestyle modification is most successful treatment (1),(7)[A]. Weight loss for those who are overweight or obese is the only therapy that ha...
Annual monitoring of LFTs (1),(7)[B]
Consider surveillance with US or CT scan to evaluate for disease progression (7)[B]. Improvements provide motivation for lifes...
Oseini AM, Sanyal AJ. Therapies in non-alcoholic steatohepatitis (NASH). Liver Int. 2017;37(Suppl 1):97–103. [View Abstract on OvidMedline]
Spengler EK, Loomba R. Recommendatio...
NAFLD is a major cause of liver disease. Spectrum ranges from NAFL to NASH, advanced fibrosis, and cirrhosis.
NAFLD is the most common chronic liver disease in children; there has been ...
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