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Floppy Iris Syndrome

Sumana Basu, MD Reviewed 04/2024
 


BASICS

DESCRIPTION

  • Intraoperative floppy iris syndrome (IFIS), a potential complication during cataract removal surgery, was first reported in 2005 and is thought to be mediated by atrophy of the iris ...

DIAGNOSIS

HISTORY

  • Inquire about use of tamsulosin, α-blockers, and other agents linked to IFIS.

  • Attention should be paid to significant comorbid conditions, including hypertension.

PHYSICAL EXAM

  • Thorough ...

TREATMENT

GENERAL MEASURES

Prior to cataract surgery, screen for any current or prior use of medications associated with IFIS (7). 

MEDICATION

First Line

  • Injection of 0.6 mL intracameral 1.5% phenylephri...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Three months postoperative observation is recommended. 

PATIENT EDUCATION

  • Patients with any degree of cataract formation who may be surgical candidates in the futur...

REFERENCES

1
González Martín-Moro  J, Muñoz Negrete  F, Lozano Escobar  I, et al. Intraoperative floppy-iris syndrome. Arch Soc Esp Oftalmol.  2013;88(2):64–76. [View Abst...

CODES

ICD10

H21.81 Floppy iris syndrome 

SNOMED

  • 418801006 intraoperative floppy iris syndrome (disorder)

  • 420545001 Tamsulosin-associated floppy iris syndrome

CLINICAL PEARLS

  • IFIS is a potential complication of cataract removal surgery.

  • Greatest risk for the development of IFIS is conferred by current or any former use of α-antagonists, especially tamsulosin...

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