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Gastric Cancer

Scott T. Henderson, MD Reviewed 06/2019
 


BASICS

DESCRIPTION

  • Malignant neoplasm occurring in the stomach

  • Infiltration to lymph nodes, omentum, lungs, and liver is rapid.

  • Uncommon in U.S. natives

  • Synonym(s): linitis plastica (“leather bottle stoma...

DIAGNOSIS

ALERT

Symptoms often present late in the disease course.

 

HISTORY

  • Assess risk factors (tobacco use; H. pylori infection, dietary history; family history of upper GI cancers or genetic syndromes...

TREATMENT

GENERAL MEASURES

  • Multidisciplinary approach

  • Surgical excision of the tumor is the only potentially curative option:

    • Extent of lymph node resection is controversial.

    • Endoscopic mucosal resectio...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Symptom-driven follow-up visits to monitor disease state, assess treatments, monitor for recurrence/metastasis, and assess nutritional status (2)[B

Patient Monitoring

REFERENCES

1
Allum WH, Blazeby JM, Griffin SM, et al; for Association of Upper Gastrointestinal Surgeons of Great Britain and Irel, British Society of Gastroenterology, British Association of Surgical ...

ADDITIONAL READING

  • Balakrishnan M, George R, Sharma A, et al. An investigation into the recent increase in gastric cancer in the USA. Dig Dis Sci.  2018;63(6):1613–1619. [View Abstract on OvidMed...

SEE ALSO

Multiple Endocrine Neoplasia (MEN) Syndromes 

CODES

ICD10

  • C16.9 Malignant neoplasm of stomach, unspecified

  • C16.8 Malignant neoplasm of overlapping sites of stomach

  • C16.2 Malignant neoplasm of body of stomach

  • C16.1 Malignant neoplasm of fundus of stom...

CLINICAL PEARLS

  • Consider gastric malignancy in patients presenting with epigastric pain and early satiety.

  • Accurate preoperative staging is necessary to determine approach to treatment and optimize sur...

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