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Gastric Cancer

Kathleen Barry, MD Reviewed 04/2024
 


BASICS

DESCRIPTION

  • Malignant neoplasm occurring in the stomach. Third most common cause of cancer-related death worldwide (1).

  • Infiltration to lymph nodes, omentum, lungs, and liver is rapid. Often dif...

DIAGNOSIS

ALERT
  • Symptoms often present late in the disease course.

  • Paraneoplastic syndromes portend poor prognosis.

 

HISTORY

  • Assess risk factors (tobacco use; H. pylori infection, dietary history; family ...

TREATMENT

GENERAL MEASURES

  • Multidisciplinary approach to identify best treatment strategy

  • Surgical excision of the tumor is the only potentially curative option:

    • Extent of lymph node resection is controv...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Symptom-driven follow-up visits to monitor disease state, assess treatments, monitor for recurrence/metastasis, and assess nutritional status 

Patient Monitoring

Mo...

REFERENCES

1
Lordick F, Carneiro F Cascinu S, et al. Gastric cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up. Annalsf Oncol. 2022;33(10): 1005-1020. doi: 10.1016/j.annon...

ADDITIONAL READING

Balakrishnan  M, George  R, Sharma  A, et al. An investigation into the recent increase in gastric cancer in the USA [published online ahead of print March 15, ...

SEE ALSO

Multiple Endocrine Neoplasia (MEN) Syndromes 

CODES

ICD10

  • C16.9 Malignant neoplasm of stomach, unspecified

  • C16.8 Malignant neoplasm of overlapping sites of stomach

  • C16.2 Malignant neoplasm of body of stomach

  • C16.1 Malignant neoplasm of fundus of stom...

CLINICAL PEARLS

  • Consider gastric malignancy in patients presenting with epigastric pain and early satiety.

  • Accurate preoperative staging is necessary to determine optimal approach to treatment and maxi...

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