Gastroesophageal Reflux Disease

Changes of the esophageal mucosa resulting from reflux of gastric contents into the esophagus

Often described as “heartburn,” “acid indigestion,” and “acid reflux”

Typical symptoms: acid regurgitation, heartburn, dysphagia (mostly postprandial)

Extraesophageal signs and symptoms: chronic cough, bronchospasm, wheezing, hoarseness, sore throat, thr...

Step-wise approach to therapy

• Phase I: lifestyle and diet modifications, antacids plus H₂ bl...

Monitor symptoms over time. Consider additional workup and/or treatment if symptoms fail to improve after 8 weeks of PPI treatment.

Repeat endosc...

K21.9 Gastro-esophageal reflux disease without esophagitis

K21.0 Gastro-esophageal reflux disease with esophagitis

235595009 Gastroesophageal reflux disease (disorder)

266433003 Gastroes...

Formal diagnosis can be achieved with a combination of endoscopy, biopsy and pH monitoring.

Consider GERD in nonsmokers with a chronic cough (>3 weeks).

PPIs provide the most rapid sy...