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Glomerulonephritis, Acute

Michael D Kolman, DO and Daniel Kniaz Reviewed 06/2022
 


BASICS

DESCRIPTION

  • Acute glomerulonephritis (GN) is an inflammatory process involving the glomerulus of the kidney, resulting in a clinical syndrome consisting of sudden-onset of hematuria, proteinuria...

DIAGNOSIS

HISTORY

  • Symptoms: cola- or tea-colored urine, decreased urine volume, blurry vision, dizziness, lightheadedness, headache, altered mentation, edema, dyspnea, generalized malaise

  • Timing

    • Poststre...

TREATMENT

GENERAL MEASURES

Treat the underlying condition if able. 

MEDICATION

First Line

  • Diuretics

  • Calcium channel blockers

  • Avoid ACE inhibitors or ARBs if acute renal dysfunction is present.

Second Line

  • Sup...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Regular blood pressure checks and urinalysis to detect recurrence, assessment of renal function to detect acute or follow chronic renal disease ...

REFERENCES

1
Wetmore JB, Guo H, Liu J, Collins AJ, Gilbertson DT. The incidence, prevalence, and outcomes of glomerulonephritis derived from a large retrospective analysis. Kidney Int. 2016 Oct;90(4):8...

SEE ALSO

  • Glomerulonephritis, Postinfectious; Henoch-Schönlein Purpura; Hyperkalemia; Hypertensive Emergencies; IgA Nephropathy; Lupus Nephritis; Nephrotic Syndrome; Vasculitis

  • Algorithm: Acute Kidney I...

CODES

ICD10

  • N00.9 Acute nephritic syndrome with unsp morphologic changes

  • N00.2 Acute nephritic syndrome w diffuse membranous glomrlneph

  • N00.8 Acute nephritic syndrome with other morphologic changes

  • N00.3 ...

CLINICAL PEARLS

  • Dysmorphic RBCs and RBC casts are a key component of the urinalysis in GN.

  • Postinfectious GN in children is typically a self-limited disease.

  • Searching for other organ involvement is use...

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