Usually history of antecedent GAS skin/throat infection
Patients present with acute nephritic syndrome, characterized by sudden onset of hematuria associated with edema and HTN for 1 t...
No specific therapy exists for PIGN, and no randomized controlled trials indicate that aggressive immunosuppressive therapy has a beneficial effect in patients with rapidly progres...
Repeat urinalysis to check for clearance of hematuria and/or proteinuria.
Consider other diagnosis if no improvement within 2 weeks.
N05.9 Unsp nephritic syndrome with unspecified morphologic changes
N00.9 Acute nephritic syndrome with unsp morphologic changes
236395002 Post-infectious glomerulonephritis (disorder)
68...
PIGN is an immune complex disease occurring after infection with certain strains of bacteria, most commonly group A Streptococcus pyogenes.
The clinical presentation can be asymptomatic...
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<bold><italic>Figure 19-11</bold> Crescentic glomerulonephritis.</bold> Crescent of epithelial cells proliferates along the parietal rim of the glomerular space and obliterates the glomerulus. Crescentic glomerulonephritis is an anatomic finding in progressively worsening glomerulonephritis of many types. Reprinted with permission from Rubin E. Pathology. 4th ed. Philadelphia. Lippincott Williams and Wilkins 2005.
<bold><italic>Figure 19-11</bold> Crescentic glomerulonephritis.</bold> Crescent of epithelial cells proliferates ...
<bold><italic>Figure 19-12</bold> Membranous glomerulonephritis (light microscopy).</bold> Basement membrane is thickened by immunoglobulin deposits.
<bold><italic>Figure 19-12</bold> Membranous glomerulonephritis (light microscopy).</bold> Basement membrane is th...
<bold>FIGURE 67-3</bold> <bold>Immune complex glomerulonephritis. A.</bold> Immunofluorescence staining of the glomerulus stained with antibodies directed against C3 showing deposits in the capillary walls and the mesangium. <bold>B.</bold> Electron micrograph of a glomerular tuft revealing electron-dense immune complex deposits in the mesangium (single arrow) and subendothelial capillary space (double arrow). The basement membrane splits to surround the subendothelial d...
<bold>FIGURE 67-3</bold> <bold>Immune complex glomerulonephritis. A.</bold> Immunofluorescence staining of the gl...