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Granuloma Inguinale

Henrique N Jaime, MD and Omar Khan, MD, FAAFP, MHS Reviewed 04/2024
 


BASICS

DESCRIPTION

Granuloma inguinale is a primarily sexually transmitted, chronic, progressive, and indolent bacterial infection caused by Klebsiella granulomatis (1) (formerly Calymmatobacterium gr...

DIAGNOSIS

HISTORY

  • Sexual contact ± genital lesions

  • Travel history is important given low prevalence in the United States.

  • History of HIV infection or other STIs

  • Subcutaneous nodules or superficial blister...

TREATMENT

Usually can be treated in an outpatient setting with appropriate antibiotics and clinical monitoring 

GENERAL MEASURES

  • Empirical treatment should be comprehensive and cover all likely pathogen...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • If treated in a timely manner, lesions usually resolve.

  • Monitor patient until resolution of symptoms.

Patient Monitoring

  • Monitor for hyperkalemia with extended TMP/S...

REFERENCES

1
Centers for Disease Control and Prevention. Granuloma Inguinale. Retrieved from https://www.cdc.gov/std/treatment-guidelines/donovanosis.htm. Last updated: July 22, 2021. Accessed February...

CODES

ICD10

A58 Granuloma inguinale 

SNOMED

  • 28867007 Granuloma inguinale (disorder)

  • 240607002 Donovanosis - inguinal lesion

  • 240606006 Donovanosis - anogenital ulcer

CLINICAL PEARLS

  • Presents as SC nodules or superficial blisters in the genital area that develop into open sores, usually painless

  • Unusual in the United States

  • The disease is transmitted usually through ...

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