Insufficient production of growth hormone (GH) in adults or children caused by problems arising in the pituitary gland and/or hypothalamus
GH is produced by somatotroph cells of the a...
Children:
Poor height velocity, slower muscular development, and delayed gross motor milestones, such as standing, walking, and jumping
Clinical questions
Birth weight and length
Prev...
GHD is treated with GH replacement.
The goal of replacement therapy is to correct the metabolic, functional, and psychological abnormalities associated with GHD.
Recombinant human gr...
Children: follow-up with a pediatric endocrinologist. Most endocrinologists will monitor growth and adjust dose every 3 to 6 months.
Childhood onset GHD: The need ...
Binder G. Growth hormone deficiency: new approaches to the diagnosis. Pediatr Endocrinol Rev. 2011;9(Suppl 1):535–537. [View Abstract on OvidMedline]
Clemmons DR. Consensus sta...
253.3 Pituitary dwarfism
253.2 Panhypopituitarism
397827003 Growth hormone deficiency (disorder)
32390006 Panhypopituitarism (disorder)
367460001 Pituitary dwarf...
Most common cause of GHD in children is idiopathic.
Most common cause of GHD in adults is a pituitary adenoma and/or treatment of the adenoma.
Most common presentation of childhood GHD i...
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