A group of acquired autoimmune disorders causing acute peripheral neuropathy and ascending paralysis that progressively worsens for up to 4 weeks followed by a slow spontaneous recov...
AIDP presents with onset of progressive limb weakness that reaches its worst within 4 weeks (73% reach a functional nadir in 1 week; 98% by 1 month).
Preceding respiratory or gastroint...
Consider admission to ensure that disease does not progress (respiratory function, autonomic stability, paralysis).
Supportive care is essential, paying close attention to com...
Patients require close monitoring of respiratory, cardiac, and hemodynamic function, typically in the ICU setting.
Pulmonary function testing (VC...
Sejvar JJ, Baughman AL, Wise M, et al. Population incidence of Guillain-Barré syndrome: a systematic review and meta-analysis. Neuroepidemiology. 2011;36(2):123–133.
Vellozzi C...
Suspect GBS in cases of ascending flaccid paralysis with areflexia and an antecedent history of viral respiratory illness or gastroenteritis.
When GBS is suspected, evaluate VC and insp...
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