Hamartoma

Gemma Kim, MD, Tae K Kim, MD and Bao T Huynh, MD Reviewed 04/2024

BASICS

DESCRIPTION

Hamartoma was first described by Albrecht in 1904.
Defined as nonneoplastic disorganized growths of native cells in native tissues
Can occur in many different organs, including bile du...

DIAGNOSIS

HISTORY

Lung hamartomas are often incidental findings on imaging and can mimic pulmonary malignancies. On imaging, e.g., chest X-ray or CT scans, masses present as coin- shaped and solitary, ...

TREATMENT

Pulmonary Hamartoma
- Wedge resection is the treatment of choice for patients with pulmonary hamartoma.
- Aggressive lobectomy or total pneumectomy is also an option in some cases.
Hypothalamic Ham...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Continued surveillance for patients at higher risk of malignancy (e.g., Peutz-Jeghers, Cowden syndromes); annual follow-up postresection of HH to assess seizure c...

REFERENCES

Yehia L, Eng C. PTEN Hamartoma Tumor Syndrome. 2001 Nov 29 [Updated 2021 Feb 11]. In: Adam MP, Mirzaa GM, Pagon RA, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Wa...

ADDITIONAL READING

OMIM: http://www.ncbi.nlm.nih.gov/omim

CODES

ICD10

Q85.9 Phakomatosis, unspecified

SNOMED

400006008 hamartoma (disorder)
254644003 hamartoma of lung (disorder)
277369003 Hamartoma of brain
268284006 vascular hamartomas (disorder)
253810002 Liver...

CLINICAL PEARLS

Hamartomas are disorganized growths of native cells in native tissues. Symptoms vary with tissue of origin; many are found incidentally.
The majority is benign; malignant transformation...

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