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Hand-Foot-and-Mouth Disease

Tyler S Rogers, MD and Shelby L Sheider, Doctor of Osteopathic Medicine Reviewed 06/2022
 


BASICS

DESCRIPTION

  • Common clinical syndrome caused by enterovirus serotypes

  • Classic appearance of oral enanthem along with exanthem of hands and feet (classically) and potentially located elsewhere

  • Exant...

DIAGNOSIS

HISTORY

  • 1- to 2-day prodrome of fever, anorexia, malaise, abdominal pain, upper respiratory symptoms

  • Fever may last 3 to 4 days.

  • Maculopapular rash on hands, feet, and mouth. Oral lesions may p...

TREATMENT

  • Symptomatic

  • Avoid spicy or acidic foods to limit oral pain.

  • IV fluids may be required in more severe cases of dehydration.

MEDICATION

ONGOING CARE

DIET

  • Encourage cold liquids (e.g., ice cream, popsicles) to prevent dehydration.

  • Avoid acidic, salty, and spicy foods, as they will increase pain.

COMPLICATIONS

  • Dehydration most common due to...

REFERENCES

1
Centers for Disease Control and Prevention. Hand, foot, and mouth disease (HFMD). http://www.cdc.gov/hand-foot-mouth/. Accessed January 5, 2018.
2
...

ADDITIONAL READING

Jones E, Pillay TD, Liu F, et al. Outcomes Following Severe Hand Foot and Mouth Disease: A Systematic Review and Meta-Analysis. Eur J Paediatr Neurol. 2018 Sep;...

CODES

ICD10

  • B08.4 Enteroviral vesicular stomatitis with exanthem

  • B34.1 Enterovirus infection, unspecified

  • B08.5 Enteroviral vesicular pharyngitis

SNOMED

  • 266108008 hand foot and mouth disease (disorder)

  • 1866...

CLINICAL PEARLS

  • Most common: May to October

  • Children <5 years of age tend to have worse symptoms than older children.

  • HFMD is the most common cause of mouth sores in pediatric patients.

  • Dehydration is...

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