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Henoch-Schönlein Purpura

Jonathan A Phillips, D.O. and Laura B Bishop, M.D. Reviewed 06/2022
 


BASICS

Increasingly referred to as Immunoglobulin-A Vasculitis (IgAV) 

DESCRIPTION

  • Henoch-Schönlein purpura (HSP) is a nonthrombocytopenic, predominantly IgA-mediated, small vessel vasculitis that affec...

DIAGNOSIS

Palpable purpura/petechiae without thrombocytopenia and at least one of the following: 
  • Diffuse abdominal pain

  • Biopsy with predominant IgA deposition

  • Arthralgia or arthritis

  • Renal involvement (h...

TREATMENT

GENERAL MEASURES

Rest and elevation of affected areas may limit purpura. Hydration and nutrition play a supportive role in treatment. 

MEDICATION

  • In the absence of renal dysfunction or complica...

ONGONIG CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Patients should be seen weekly during the acute illness. Visits should include history, physical exam (include BP measurement), and urinalysis.

  • B...

REFERENCES

1
Kutlubay  Z, Zara  T, Engin  B, et al. Helicobacter pylori infection and skin disorders. Hong Kong Med J.  2014; 20(4): 317– 324.  [View Abstract] ...

ADDITIONAL READING

  • Batu  ED, Ozen  S. Pediatric vasculitis. Curr Rheumatol Rep.  2012; 14(2): 121– 129.  [View Abstract]

  • ...

CODES

ICD10

D69.0 Allergic purpura 

SNOMED

  • 191306005 Henoch-Schonlein purpura (disorder)

  • 239946005 Postinfective Henoch-Schnlein purpura

CLINICAL PEARLS

  • HSP is a systemic small vessel vasculitis characterized by clinical tetrad of palpable purpura, abdominal pain, arthralgia, and renal dysfunction.

  • The main form of treatment is supporti...

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