Heparin-Induced Thrombocytopenia

A life-threatening complication of heparin use

• Platelet count falls between 30% and 50% from baseline.

Antibody-mediated prothrombotic disorder initiated by heparin administration

Unlik...

Nonimmune heparin-associated thrombocytopenia (HIT): asymptomatic drop in platelet count

HITT: thrombocytopenia or thrombosis with the presence of heparin-dependent antibodies

• The foundation f...

Discontinue all heparin...

The transition period of anticoagulation with a DTI and warfarin in patients with HIT can be problematic.

The INR while administering both a DTI and warfarin shoul...

Chaudhary RK, Nepal C, Khanal N, et al. Management and outcome of heparin-induced thrombocytopenia in pregnancy: a systematic review. Cardiovasc Hematol Agents Med Chem.  2015;...

73397007 Heparin-induced thrombocytopenia (disorder)

111588002 Heparin-induced thrombocy...

Heparin exposure through any preparation (including LMWH), any dose, or any route can cause HITT, a life-threatening condition that is associated with severe and extensive thromboembol...