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Hepatitis C

Christopher Lin-Brande, MD and Jason C. McCarthy, MD Reviewed 06/2018
 


BASICS

DESCRIPTION

Systemic viral infection (acute and chronic) primarily involving liver 

EPIDEMIOLOGY

  • Highest incidence ages 20 to 39 years; highest prevalence between 40 and 59 years of age

  • Males and n...

DIAGNOSIS

HISTORY

  • Determine exposure risk: detailed social history including alcohol and IV drug use, psychiatric and medical comorbidities, coinfections.

  • Chronic HCV: Most cases are mildly symptomatic ...

TREATMENT

GENERAL MEASURES

  • Report acute HCV to health department.

  • Treat all patients with virologic evidence of HCV.

  • Pretreatment counseling includes a thorough behavioral health and substance abuse hist...

ONGOING CARE

FOLLOW UP RECOMMENDATIONS

  • Treat early to prevent fibrosis. If cirrhosis is present, treatment may not prevent decompensation.

  • Monitor serial viral load only if on antiviral therapy.

  • Some exp...

REFERENCES

1
Denniston MM, Jiles RB, Drobeniuc J, et al. Chronic hepatitis C virus infection in the United States, National Health and Nutrition Examination Survey 2003 to 2010. Ann Intern Med.  2...

SEE ALSO

CODES

ICD10

  • B19.20 Unspecified viral hepatitis C without hepatic coma

  • B17.10 Acute hepatitis C without hepatic coma

  • B18.2 Chronic viral hepatitis C

ICD9

  • 070.70 Unspecified viral hepatitis C without hepatic...

CLINICAL PEARLS

  • 1 of every 10 patients with hepatitis C has no identifiable risk factors.

  • 15–25% of HCV-infected persons spontaneously resolve the infection without specific treatment.

  • Look for coinfect...

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