In children
Feminization, precocious puberty
Palpable liver mass, pain, asymmetrical hepatomegaly
In adults
Known cirrhosis or clinical signs of cirrhosis: 80%
Abdominal pain: 80%; right uppe...
Targeted therapy with sorafenib offers a small survival benefit in patients with disease not amenable to surgical intervention; not effective as adjunctive to surgery (7)[B]
Treatme...
AFP level every 3 months
US every 4 to 6 months or contrast-enhanced CT/MRI ...
American Cancer Society. Cancer facts & figures 2015: http://www.cancer.org/research/cancerfactsstatistics/cancerfactsfigures2015/index. Accessed February 7, 2019. http://www.ca...
With benign liver tumors, most patients will have normal LFTs; 97% with HCC will have >1 abnormal test.
Hepatitis C is the greatest risk factor, especially if combined with alcohol a...
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Gallstones