Highly infectious viral disease caused most commonly by viruses within the Picornavirus family. This most commonly includes coxsackievirus, other enteroviruses, echovirus and human r...
Fever of relatively sudden onset
General malaise, anorexia, irritability, listlessness
Sore throat, painful oral lesions, drooling, coryza
Neck pain, headache, back pain
Diarrhea
Benign, self-limited course
Symptoms typically abate in less than a week.
Symptomatic treatment
Frequent handwashing
Palliative and supportive care; emphasize hydration
No restrictions
As tolerated, with no limitations
Clear liquids
Cold beverages, milk, and ice cream are soothing. Hot, acidic beverages can be irritating.
Jubelt B, Lipton HL. Enterovirus/picornavirus infections. Handb Clin Neurol. 2014;123:379-416. doi: 10.1016/B978-0-444-53488-0.00018-3. PMID: 25015496. ...
Herpangina occurs most commonly during summer months in children.
Coxsackievirus and other enterovirus are the most common causes of herpangina.
Proper hand hygiene protects against spre...
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FIG. 11.8. Coxsackie hand-foot-and-mouth disease. A: A hand and a foot of this child show isolated vesicles compared with the grouped vesicles seen in the patient in Figure 11.7 with a herpetic infection. The child also had palatal lesions. B: Scattered petechiae appear centrally, and there is a vesicle posteriorly at the junction of the hard and soft palates. Coxsackievirus produces lesions toward the posterior of the oropharynx, whereas herpes simplex virus appears anteriorly.
FIG. 11.8. Coxsackie hand-foot-and-mouth disease. A: A hand and a foot of this child show isolated vesicles compared with the grouped vesi...
<bold>Figure 20-2</bold> Herpangina. (Courtesy of Paul S. Matz, MD.)
<bold>Figure 26-3</bold> Herpangina. (Courtesy of Philip Siu, MD.)
herpangina
Hand-foot-mouth disease in a young child with fever and irritability