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HIV/AIDS

Carol Hungerford, DO and Pamela Hughes, MD Reviewed 06/2018
 


BASICS

DESCRIPTION

  • HIV is a retrovirus (subgroup lentivirus) that integrates into CD4 T-lymphocytes, altering cell-mediated immunity and causing cell death, severe immunodeficiency, opportunistic infec...

DIAGNOSIS

  • Acute retroviral syndrome: CD4 lymphocyte count declines with increase in viral load 1 to 4 weeks after transmission; confirmed by high-HIV RNA in the absence of HIV antibody

  • Acute retroviral...

TREATMENT

  • Initiate ART in patients meeting eligibility requirements. Select/change regimens based on resistance testing.

  • Consider dosing frequency, pill burden, adverse toxic effect profiles, comorbidi...

ONGOING CARE

FOLLOW UP RECOMMENDATIONS

Patient Monitoring

  • If HIV RNA is detectable at 2 to 8 weeks, repeat every 4 to 8 weeks until suppressed to less than level of detection and then follow every 3 to ...

REFERENCES

1
Center for Disease Control and Prevention. HIV/AIDS basic statistics. Updated September 22, 2017. https://www.cdc.gov/hiv/basics/statistics.html. Accessed October 11, 2017.
2
U.S. Department...

ADDITIONAL READING

Centers for Disease Control and Prevention. Statistics overview: HIV surveillance report. http://www.cdc.gov/hiv/statistics/overview/index.html. Accessed October 06, 2017. 

CODES

ICD10

  • Z21 Asymptomatic human immunodeficiency virus infection status

  • B20 Human immunodeficiency virus [HIV] disease

  • R75 Inconclusive laboratory evidence of human immunodef virus

  • Z20.6 Contact w and ...

CLINICAL PEARLS

  • Acute HIV seroconversion illness mimics mononucleosis and is characterized by fever, sore throat, adenopathy, myalgias, and rash.

  • Transmitted drug resistance is increasing. Evaluate pat...

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