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Hodgkin Lymphoma

Prarthna V Bhardwaj, MBBS and Doyun Park, MD Reviewed 05/2023
 


BASICS

Hodgkin Lymphoma (HL) is a neoplasm of the lymphatic system representing one of the common cancers in young adults. Characterized by a low number of malignant cells deriving from B-lymphocytes ...

DIAGNOSIS

HISTORY

  • Painless lymphadenopathy (cervical/supraclavicular)

  • Pel-Ebstein (cyclic) fever—high-grade fever every 7–10 days

  • Constitutional symptoms or “B symptoms”: drenching night sweats, profound...

TREATMENT

  • Ann Arbor staging with Cotswold modification

    • Stage I: single lymph node or of a single extralymphatic organ or site

    • Stage II: ≥2 lymph node regions on the same side of diaphragm alone or with ...

ONGOING CARE

Patients treated with ABVD become neutropenic. Treatment is continued despite neutropenia with no clear increased risk of infection with or without growth factors. 

FOLLOW-UP RECOMMENDATIONS

REFERENCES

1
Barrington  SF, Kirkwood  AA, Franceschetto  A, et al. PET-CT for staging and early response: results from the Response-Adapted Therapy in Advanced Hodgkin Lymphoma...

CODES

ICD10

  • C81.96 Hodgkin lymphoma, unspecified, intrapelvic lymph nodes

  • C81.44 Lymphocyte-rich Hodgkin lymphoma, lymph nodes of axilla and upper limb

  • C81.75 Other Hodgkin lymphoma, lymph nodes of ingui...

CLINICAL PEARLS

  • Hodgkin's lymphoma mainly affects young people.

  • It is a potentially curable lymphoma. Treatment includes chemotherapy +/- radiation therapy.

  • If patient develops neutropenia during treatm...

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