Huntington Disease

Hereditary neurodegenerative disease characterized by progressive motor, cognitive, and psychiatric symptoms

• Onset of symptoms typically occurs between age 30 and 50

• Average survival 1...

Patients with an affected family member may present requesting investigation in the presymptomatic stage.

Physical symptoms are typically noted first, presenting with choreiform moveme...

Genetic counseling prior to testing and for children of those with confirmed disease

Speech, swallow, occupational, and physical therapy to preserve maximal function

Psychiatri...

Full activity as long as possible

Physical therapy (6)

• Aerobic exercise alone or in combination with resistance training

• Supervised gait training

• Breathing exercises...

58756001 Huntington's chorea (disorder)

230299004 Juvenile onset Huntington's disease

230300007 Late onset Huntington's disease

230301006 Akinetic-rigid form of ...

HD is an autosomal dominantly inherited disease of insidious onset (typically) between 30 and 50 years.

There is no known cure, with life expectancy 10–20 years after clinical diagnosis...