Huntington Disease

Inherited neurodegenerative disease characterized by progressive motor and psychiatric dysfunction, dementia, and ultimately death

• Onset of symptoms typically occurs between 30 and 50...

Patients with an affected family member may present requesting investigation in the presymptomatic stage.

Physical symptoms are typically noted first. Patients may present with choreif...

Genetic counseling

Speech, swallow, occupational, and physical therapy to preserve maximal function

Psychiatric/psychological consultation

Feeding tubes and smoking cessation in...

Full activity as long as possible

Physical therapy:

• Balance and walking problems

• Strength-building exercises

• Exercise to help combat depression

Occupational therapy

• Hom...

Reilmann R. Pharmacological treatment of chorea in Huntington's disease—good clinical practice versus evidence-based guideline. Mov Disord.  2013;28(8):1030–1033.

Ross CA, Tabri...

58756001 Huntington's chorea (disorder)

230299004 Juvenile onset Huntington's disease

230300007 Late onset Huntington's disease

230...

HD is an autosomal dominantly inherited disease of insidious onset (typically) between 30 and 50 years.

There is no known cure.

Early symptoms include rhythmic choreiform movements, dyst...