Skip to main content

Hyperparathyroidism

Michael Morkos, MD, MS Reviewed 06/2018
 


BASICS

DESCRIPTION

A dysfunction of the body’s normal regulatory feedback mechanisms resulting in excess production of parathyroid hormone (PTH) 
  • Primary hyperparathyroidism (HPT): intrinsic parathyroid...

DIAGNOSIS

HISTORY

  • History of present illness

    • Almost 80% of patients are asymptomatic

    • Kidney stones (15–20%)

    • Osteitis fibrosa cystica (<5%) characterized by subperiosteal resorption of phalanges, tape...

TREATMENT

MEDICATION

  • Primary HPT: Operative management is curative, indications for surgical intervention are mentioned below. For those awaiting or unable to have surgery:

    • Bisphosphonates (alendronat...

ONGOING CARE

FOLLOW UP RECOMMENDATIONS

Asymptomatic patients with primary HPT require serial monitoring of calcium and PTH. 

Patient Monitoring

In patients with primary HPT who are asymptomatic, measurem...

REFERENCES

1
Bilezikian JP, Brandi ML, Eastell R, et al. Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the Fourth International Workshop. J Clin Endo...

CODES

ICD10

  • E21.3 Hyperparathyroidism, unspecified

  • E21.0 Primary hyperparathyroidism

  • E21.1 Secondary hyperparathyroidism, not elsewhere classified

  • E21.2 Other hyperparathyroidism

ICD9

  • 252.00 Hyperparathyroi...

CLINICAL PEARLS

  • 80% of patients with primary HPT are asymptomatic.

  • HPT is often detected by an incidental finding of hypercalcemia on a routine serum chemistry analysis.

  • Classic symptoms of HPT include ...

Subscribe to Access Full Content

Sign Up for a 10-Day Free Trial

Sign up for a 10-day FREE Trial now and receive full access to all content.

×