Primary hyperparathyroidism (HPT): intrinsic parathyroid gland dysfunction resulting in excessive secretion of PTH with a lack of respo...
Almost 80% of patients are asymptomatic.
Kidney stones (15–20%)
Osteitis fibrosa cystica (<5%) characterized by subperiosteal resorption of phalanges, tape...
Primary HPT: Operative management is curative; indications for surgical intervention are mentioned below. For those awaiting or unable to have surgery:
Bisphosphonates (alendronate)...
Bilezikian JP. Primary hyperparathyroidism. J Clin Endocrinol Metab. 2018;103(11):3993-4004. doi:10.1210/jc.2018-01225
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E21.3 Hyperparathyroidism, unspecified
N25.81 Secondary hyperparathyroidism of renal origin
E21.1 Secondary hyperparathyroidism, not elsewhere classified
E21.0 Primary hyperparathyroidism
E21.2...
80% of patients with primary HPT are asymptomatic.
HPT is often detected by an incidental finding of hypercalcemia on a routine serum chemistry analysis.
Classic symptoms of HPT include ...
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