Hypersplenism is defined as overactivity of the spleen and presents as the following:
Splenomegaly (commonly but not always)
Cytopenias with respective bone marrow hyperplasia of precu...
Patients may complain of abdominal fullness or protrusion of the spleen through the abdominal wall; may complain of early satiety if the spleen is compressing stomach
Patients may comp...
No specific medication can be recommended for patients with hypersplenism. The most important intervention is to treat the underlying disorder.
If ITP is the cause, the patient may ...
Adult patients who are splenectomized should be advised to monitor closely for fever or rigors at home, which may be an early sign of bacteremia. They should be instructed to begin antibi...
D73.1 Hypersplenism
58381000 Hypersplenism
Splenectomy is not necessary to make the diagnosis.
Avoid splenectomy in patients unless absolutely necessary. Splenectomized patients are at lifelong risk for overwhelming postsplenect...
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FIGURE 20.3. Chest radiograph (posteroanterior view only) demonstrating the radiographic presentation of miliary tuberculosis.
FIGURE 20.4. Chest radiographs (posteroanterior and lateral views) demonstrating cavitary reactivation of latent tuberculosis infection in the posterior apical segment of the right upper lobe.
FIGURE 20.4. Chest radiographs (posteroanterior and lateral views) demonstrating cavitary reactivation of latent tuberculosis infection in...
Figure 189.1. Chest radiograph demonstrating apical infiltrate with cavitation, typical of pulmonary tuberculosis.
Figure 16.17. A thin blood smear shows several P. falciparum-infected erythrocytes. One erythrocyte has a ring form along its edge (appliqué form), and the other has a ring form that contains double dots of chromatin (arrow). Giemsa, 3400.
Figure 16.17. A thin blood smear shows several P. falciparum-infected erythrocytes. One erythrocyte has a ring form along its edge (appli...
Figure 16.24. A blood film from a patient with P. vivax infection shows two microgametocytes and several ring forms. The microgametocytes have large nuclei with loose chromatin (arrow). Giemsa, 3400.
Figure 16.24. A blood film from a patient with P. vivax infection shows two microgametocytes and several ring forms. The microgametocytes...
FIG. 10.15. Hemorrhagic bullae of the lips (A) and petechiae on the tongue (B) mark the presentation of this child with idiopathic thrombocytopenic purpura.
FIG. 10.15. Hemorrhagic bullae of the lips (A) and petechiae on the tongue (B) mark the presentation of this child with idiopathic thrombo...
Necrotizing granuloma due to M. tuberculosis. A small tuberculous granuloma with conspicuous central caseation is present in the pulmonary parenchyma.
Necrotizing granuloma due to M. tuberculosis. A small tuberculous granuloma with conspicuous central caseation is present in the pulmonary...
Cavitary tuberculosis. The apex of the left upper lobe shows tuberculous cavities surrounded by consolidated and fibrotic pulmonary parenchyma, which contains small tubercles.
Cavitary tuberculosis. The apex of the left upper lobe shows tuberculous cavities surrounded by consolidated and fibrotic pulmonary parenc...
Miliary tuberculosis. Multiple millimeter-sized nodules are scattered throughout the lung parenchyma.
Idiopathic thrombocytopenic purpura. A section of the bone marrow reveals increased megakaryocytes.
Tuberculous spondylitis (Pott disease). A vertebral body is almost completely replaced by tuberculous tissue. Note the preservation of the intervertebral discs.
Tuberculous spondylitis (Pott disease). A vertebral body is almost completely replaced by tuberculous tissue. Note the preservation of the...
Mycobacterium tuberculosis. A smear of a pulmonary lesion shows slender, beaded, acid-fast bacilli.
Life cycle of malaria. An Anopheles mosquito bites an infected person, taking blood that contains micro- and macrogametocytes (sexual forms). In the mosquito, sexual multiplication ("sporogony") produces infective sporozoites in the salivary glands. (1) During the mosquito bite, sporozoites are inoculated into the bloodstream of the vertebrate host. Some sporozoites leave the blood and enter the hepatocytes, where they multiply asexually (exoerythrocytic schizogony), and form thousands of u...
Life cycle of malaria. An Anopheles mosquito bites an infected person, taking blood that contains micro- and macrogametocytes (sexual form...
Immune Hemolytic Anemia White cells May be elevated due to an increased in neutrophils Counts may approach 30 X 10<sup>9</sup> /L Platelets Usually normal Red cells Hb and Hct decreased Normocytic, normochromic anemia Reticulocytes increased Increased MCV is due to prominent reticulocytosis Spherocytes Bone marrow Hypercellular with erythroid precursors Peripheral Smear
Immune Hemolytic Anemia White cells May be elevated due to an increased in neutrophils Counts may approach 30 X 10<sup>9</...
FIG. 10.15. Hemorrhagic bullae of the lips (A) and petechiae on the tongue (B) mark the presentation of this child with idiopathic thromboc...
<bold>Figure 67-8</bold> Petechiae and ecchymoses in a patient with idiopathic thrombocytopenic purpura. (Courtesy of Sidney Sussman, MD.)
<bold>Figure 67-8</bold> Petechiae and ecchymoses in a patient with idiopathic thrombocytopenic purpura. (Courtesy of Sidney Su...