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Hypersplenism

Reviewed 06/2018
 


BASICS

DESCRIPTION

  • Hypersplenism is defined as overactivity of the spleen and presents as the following:

    • Splenomegaly (commonly but not always)

    • Cytopenias with respective bone marrow hyperplasia of pre...

DIAGNOSIS

HISTORY

  • Patients may complain of abdominal fullness or protrusion of the spleen through the abdominal wall; may complain of early satiety if the spleen is compressing stomach

  • Patients may comp...

TREATMENT

MEDICATION

  • No specific medication can be recommended for patients with hypersplenism. The most important intervention is to treat the underlying disorder.

  • If ITP is the cause, the patient may ...

ONGOING CARE

  • Adult patients who are splenectomized should be advised to monitor closely for fever or rigors at home, which may be an early sign of bacteremia. They should be instructed to begin antibi...

REFERENCES

1
Bai YN, Jiang H, Prasoon P. A meta-analysis of perioperative outcomes of laparoscopic splenectomy for hematological disorders. World J Surg.  2012;36(10):2349–2358. [View Abstract on...

ADDITIONAL READING

  • Abdella HM, Abd-El-Moez AT, Abu El-Maaty ME, et al. Role of partial splenic arterial embolization for hypersplenism in patients with liver cirrhosis and thrombocytopenia. Indian J G...

SEE ALSO

Anemia, Autoimmune Hemolytic; Malaria; Polycythemia Vera; Tuberculosis 

CODES

ICD10

D73.1 Hypersplenism 

ICD9

289.4 Hypersplenism 

SNOMED

  • 58381000 Hypersplenism (disorder)

  • 420749009 Hypersplenism associated with acquired immunodeficiency syndrome (disorder)

CLINICAL PEARLS

  • Splenectomy is not necessary to make the diagnosis.

  • Avoid splenectomy in patients unless absolutely necessary. Splenectomized patients are at lifelong risk for overwhelming postsplenect...

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