Skip to main content

Hypertriglyceridemia

S. Lindsey Clarke, MD, FAAFP Reviewed 06/2020
 


BASICS

DESCRIPTION

  • Hypertriglyceridemia (HTG) is a common form of dyslipidemia characterized by an excess fasting plasma concentration of triglycerides (TGs).

    • TGs are fatty molecules that occur naturall...

DIAGNOSIS

HISTORY

  • Usually asymptomatic

  • Patients with chylomicronemia syndrome can have memory loss, headache, vertigo, dyspnea, and paresthesias.

  • Pancreatitis: epigastric pain, nausea, and vomiting

  • Assess...

TREATMENT

GENERAL MEASURES

  • Cardiovascular risk reduction through LDL lowering should be prioritized over TG lowering unless patient is at risk for pancreatitis because of very high TG (≥500 mg/dL) (1)[...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

2 months after initiation or modification of therapy (repeat fasting lipid profile) 

Patient Monitoring

  • Fasting lipid profile q6–12mo

  • Maintain TG <500 to 1,000 mg...

REFERENCES

1
Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: a report of the American College of Ca...

ADDITIONAL READING

  • Jellinger PS, Handelsman Y, Rosenblit PD, et al. American Association of Clinical Endocrinologists and American College of Endocrinology guidelines for management of dyslipidemia an...

CODES

ICD10

E78.1 Pure hyperglyceridemia 

ICD9

272.1 Pure hyperglyceridemia 

SNOMED

  • 302870006 Hypertriglyceridemia (disorder)

  • 238083002 Primary hypertriglyceridemia (disorder)

  • 238087001 secondary hypertrigly...

CLINICAL PEARLS

  • HTG is a risk factor for atherosclerosis at levels ≥175 mg/dL and for acute pancreatitis at levels ≥500 to 1,000 mg/dL.

  • Therapeutic lifestyle interventions (diet and exercise) are recom...

Subscribe to Access Full Content

Sign Up for a 10-Day Free Trial

Sign up for a 10-day FREE Trial now and receive full access to all content.

 
×