Hypoglycemia, Nondiabetic

Hypoglycemia defined by the Whipple triad

• Low plasma glucose level (≤60 mg/dL) with hypoglycemic symptoms that are relieved when glucose is corrected

• Occurs commonly in patients with...

CNS (neuroglycopenic) symptoms predominate with gradual glucose reduction:

• Headache

• Confusion

• Light-headedness

• Fatigue and weakness

• Visual disturbances

• Changes in personality

Adrenergic sy...

Outpatient except for severe cases; may also be inpatient for testing

Oral carbohydrate for alert patient without drug overdose (2 to 3 tbsp of sugar in glass of water or frui...

Exercise routine or daily activity may need to be reevaluated.

Patients with recurrent hypoglycemia should have glucose source at hand for immediate ingestion duri...

Cansu DU, Korkmaz C. Hypoglycaemia induced by hydroxychloroquine in a non-diabetic patient treated for RA. Rheumatology (Oxford).  2008;47(3):378–379. [View Abstract on OvidMe...

Hypoglycemia, Diabetic; Insulinoma

Algorithm: Hypoglycemia

E16.2 Hypoglycemia, unspecified

E16.1 Other hypoglycemia

P70.4 Other neonatal hypoglycemia

E16.0 Drug-induced hypoglycemia without coma

251.2 Hypoglycemia, unspecified

579.3 Other and unspec...

Symptoms coincide with low-blood glucose levels and resolve with PO/IV glucose or glucagon.

Avoid known agents/nutrients that trigger hypoglycemia.

Treat underlying cause.