Neoplasm of the pancreatic β cells of the islets of Langerhans leading to hyperinsulinemia. Pancreatic β cells manufacture proinsulin, which is then cleaved into insulin and C-peptid...
Symptoms are typically vague and periodic which can result in a delay in diagnosis of, on average, 18 months (3,6).
Symptoms are often worsened with fasting or exercise but can occur ...
Definitive treatment is surgical removal, usually by enucleation (8).
Medications can be used to help stabilize blood sugars in patients awaiting surgery, those with metastatic disease, or i...
Multiple Endocrine Neoplasia (MEN) Syndromes
Algorithm: Hypoglycemia
D13.7 Benign neoplasm of endocrine pancreas
C25.4 Malignant neoplasm of endocrine pancreas
D37.8 Neoplasm of uncertain behavior of oth digestive organs
302822000 Insulinoma (disorder)
254...
Conduct a C-peptide test if a patient is suspected of self-administering insulin or oral hypoglycemics to mimic symptoms of insulinoma. Proinsulin levels are not elevated with self-adm...
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