Kallmann syndrome (KS) is hypogonadotropic hypogonadism caused by deficient gonadotropin-releasing hormone (GnRH).
Patients present with incomplete or absent puberty, infertility, and...
Both genders will display delayed sexual maturation, but the classic presentations differ depending on gender.
Female patients: primary amenorrhea and history of multiple fractures
Ma...
There are multiple management approaches and individual patient considerations that must be taken into account in determining an appropriate course.
In chronic GnRH deficiency, patients may d...
Patients with autosomal dominant form o...
93559003 hypogonadism with anosmia (disorder)
33927004 Hypogonadotropic hypogonadism (disorder)
123953004 Idiopathic h...
KS represents a specific variant of hypogonadotropic hypogonadism resulting from failed migration of hypothalamic neurons from the olfactory placode during embryologic development.
KS s...
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