Kawasaki syndrome (KS) is a self-limited acute, febrile, systemic vasculitis of small- and medium-sized arteries that predominantly affects patients age 6 months to 5 years
The most ...
≥5 days of fever and ≥4 of the following five principal clinical features (1); OR <4 features and presence of coronary artery disease on 2D echocardiography:
Bilateral, nonpurul...
Optimal therapy is IVIG 2 g/kg IV over 10 to 12 hours with high-dose aspirin p...
Repeat ECG and echocardiogram at 6 to 8 weeks. If abnormal, repeat at 6 to 12 mo...
Most ZM, Hendren N, Drazner MH, et al. The striking similarities of multisystem inflammatory syndrome in children and a myocarditis-like syndrome in adults: overlapping m...
The diagnosis of KS rests on a constellation of clinical features.
Once KS is suspected, all patients need an inpatient cardiac evaluation, including ECG and echocardiogram.
Optimal ther...
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FIGURE 101.14. Lead III from an electrocardiogram on a 15-month-old boy showing deep Q waves in Kawasaki disease.
FIG. 2.19. Clinical findings in Kawasaki disease. A: Cracked, erythematous lips, and "strawberry" tongue in Kawasaki disease. B: Brawny edema of the dorsum of the hand and small joint polyarthritis in Kawasaki disease. C: Peeling of the skin on the thumbs in Kawasaki disease.
FIG. 2.19. Clinical findings in Kawasaki disease. A: Cracked, erythematous lips, and "strawberry" tongue in Kawasaki disease. B: Brawny ed...
<bold>Figure 38-1</bold> Kawasaki disease. Swelling, erythema, and tenderness develop in the hands of this 4-year-old a few days after onset of high fever. (Courtesy of Mark A. Ward, MD.)
<bold>Figure 38-1</bold> Kawasaki disease. Swelling, erythema, and tenderness develop in the hands of this 4-year-old a few ...
<bold>Figure 47-6</bold> Foot edema and erythema in a child with Kawasaki disease. (Courtesy of Esther K. Chung, MD.)
<bold>Figure 65-4</bold> Kawasaki disease. Erythematous maculopapular rash that started in groin and spread onto trunk. (Courtesy of George A. Datto, III, MD.)
<bold>Figure 65-4</bold> Kawasaki disease. Erythematous maculopapular rash that started in groin and spread onto trunk. (Court...
<bold>FIGURE 10-33. Kawasaki disease.</bold><bold>A.</bold> The heart of a child who died from Kawasaki disease shows conspicuous coronary artery aneurysms. <bold>B.</bold> A microscopic section of a coronary artery from the same patient shows two large defects <italic>(arrows)</bold> in the internal elastic lamina, with two small aneurysms filled with thrombus.
<bold>FIGURE 10-33. Kawasaki disease.</bold><bold>A.</bold> The heart of a child who died from Kawasaki disease sh...
Kawasaki disease. The heart of a child who died from Kawasaki disease shows conspicuous coronary artery aneurysms.
<bold>FIGURE 26-29</bold> Kawasaki disease. (<bold>A</bold>) Rash of Kawasaki disease in a 7-month-old child on the 4th day of illness; (<bold>B</bold>) conjunctival injection, lip edema in a 2-year-old boy on the 6th day of illness; (<bold>C</bold>) erythema and edematous hand of a 1½-year-old girl on the 6th day of illness; and (<bold>D</bold>) periungual desquamation in a 3-year-old child on the 12th day of illness.
<bold>FIGURE 26-29</bold> Kawasaki disease. (<bold>A</bold>) Rash of Kawasaki disease in a 7-month-old child on th...