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Laryngeal Cancer

Karlynn Sievers, MD and Sara Warzecka, MD Reviewed 04/2024
 


BASICS

DESCRIPTION

  • A friable, granular squamous cell carcinoma of the larynx that leads to hoarseness, hemoptysis, and cough

  • System(s) affected: pulmonary; ear, nose, throat (ENT)

  • Synonym(s): cancer of t...

DIAGNOSIS

  • Early laryngeal cancer diagnosis generally has a 5-year disease-specific survival rate of 59-83% when found in the localized stage, depending on its location (supraglottic, glottic, or subgl...

TREATMENT

  • Early laryngeal cancer (e.g., stage I or II) is often treated with single-modality therapy; no difference in overall survival between radiation therapy (XRT), open surgery, and endoscopic su...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • Patient may remain fully active unless debilitated from more advanced disease and/or greater degree of surgery.

  • Reasons for posttreatment follow-up:

    • Evaluation of t...

REFERENCES

1
Warner  L, Chudasama  J, Kelly  CG, et al. Radiotherapy versus open surgery versus endolaryngeal surgery (with or without laser) for early laryngeal squamous cell c...

CODES

ICD10

  • C32.9 Malignant neoplasm of larynx, unspecified

  • C32.8 Malignant neoplasm of overlapping sites of larynx

  • C32.3 Malignant neoplasm of laryngeal cartilage

  • C32.0 Malignant neoplasm of glottis

  • C32.1...

CLINICAL PEARLS

  • Persistent hoarseness in an at-risk older person should prompt investigation with indirect and/or direct laryngoscopy.

  • XRT and multimodal therapies have reduced the need for laryngectom...

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