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Leishmaniasis

Garrett W. Huck, MD Reviewed 06/2018
 


BASICS

A clinically diverse group of infections caused by protozoa of the genus Leishmania (transmitted by a bite from an infected female sandfly), ranging from a single self-healing ulcer (cutaneous)...

DIAGNOSIS

Signs and symptoms consistent with leishmaniasis in individuals from an endemic area or history of travel to an endemic area: chronic cutaneous ulcer; acutely febrile patients; fulminant dis...

TREATMENT

  • Treat under the supervision of, or in consultation with, a physician experienced in the management of leishmaniasis.

    • Contact the CDC at (800) CDC-INFO (800-232-4636) or 404-718-4745 (HCPs onl...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Follow up at 6 weeks, 3 months, and 12 months to evaluate treatment effectiveness and to detect relapses.

    • Lesion size should decrease by 2/3 by 6...

REFERENCES

1
Alvar J, Vélez ID, Bern C, et al. Leishmaniasis worldwide and global estimates of its incidence. PLoS One.  2012;7(5):e35671. [View Abstract on OvidMedline]
2
Srivastava P, Dayama A, Me...

ADDITIONAL READING

  • Cota GF, de Sousa MR, Demarqui FN, et al. The diagnostic accuracy of serologic and molecular methods for detecting visceral leishmaniasis in HIV infected patients: meta-analysis. PL...

CODES

ICD10

  • B55.9 Leishmaniasis, unspecified

  • B55.1 Cutaneous leishmaniasis

  • B55.0 Visceral leishmaniasis

  • B55.2 Mucocutaneous leishmaniasis

ICD9

  • 085.9 Leishmaniasis, unspecified

  • 085.4 Cutaneous leishmaniasis, ...

CLINICAL PEARLS

  • A nonhealing cutaneous ulcer in a patient with the appropriate history of travel to endemic area is leishmaniasis until proven otherwise.

  • Consider VL in febrile travelers with organomeg...

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