A chronic, inflammatory granulomatous infection (caused by Mycobacterium leprae, a slow-growing, acid-fast bacillus, and similar, recently discovered M. lepromatosis), preferentially...
Known or suspected contact with leprosy; immigrant from high-incidence country (India, Brazil, Indonesia, Nepal)
Skin lesions and/or enlarged nerves accompanied by sensory loss
Ulcers i...
Multidisciplinary approach, including orthopedic surgery, ophthalmology, and physical therapy in addition to specific drug therapy
Rigid-soled footwear, walking plaster casts,...
Frequent follow-up visits until therapy is stabilized and then monthly supervision
Drug toxicity uncommon after 1st year of treatment
CBC, renal, ...
A30.9 Leprosy, unspecified
A30.0 Indeterminate leprosy
A30.1 Tuberculoid leprosy
A30.3 Borderline leprosy
A30.2 Borderline tuberculoid leprosy
A30.4 Borderline lepromatous leprosy
A30.5 Lepromato...
Most humans (95%) are notsusceptible to leprosy.
There are no serologic or skin tests for screening or early diagnosis of leprosy before physical signs are present.
In suspected cases, t...
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Figure 158.11. Moderately advanced lepromatous (LL) leprosy. There is symmetric infiltration of the face with particular involvement of the eyebrows, nose, and cheek creases. Eyebrow loss (madarosis is also present).
Figure 158.11. Moderately advanced lepromatous (LL) leprosy. There is symmetric infiltration of the face with particular involvement of th...
Facial deformities in a Korean leprosy patient. Madarosis, bilateral lagophthalmos with lateral tarsorrhaphies, total corneal opacity from exposure, nasal destruction.
Facial deformities in a Korean leprosy patient. Madarosis, bilateral lagophthalmos with lateral tarsorrhaphies, total corneal opacity from...
(A, top) Lepromatous leprosy. There is diffuse involvement, including a leonine face, loss of eyebrows and eyelashes, and nodular distortions, especially on the face, ears, forearms, and hands - the exposed (cool) parts of the body. (A, bottom) The nodular skin lesions of advanced lepromatous leprosy. Swelling has flattened the epidermis (loss of Rete ridges). A characteristic "clear zone" of uninvolved dermis separates the epidermis from tumor-like accumulations of macrophages, each contai...
(A, top) Lepromatous leprosy. There is diffuse involvement, including a leonine face, loss of eyebrows and eyelashes, and nodular distorti...
lepromatous leprosy
Hands of patient in Fig. 44.1, which show deformities.