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Leriche Syndrome

Melissa Jefferis, MD, FAAFP and Shelby M. Reimer, MD Reviewed 06/2019
 


BASICS

DESCRIPTION

Leriche syndrome, also known as aortoiliac occlusive disease, is the constellation of symptoms caused by atherosclerotic stenosis of the abdominal aorta as it bifurcates into the ili...

DIAGNOSIS

HISTORY

  • Male: erectile or ejaculatory dysfunction (1)

  • Intermittent claudication symptoms: cramping or atypical pain in thighs, hips, and buttocks exacerbated by walking and relieved with rest

  • R...

TREATMENT

GENERAL MEASURES

  • Smoking cessation is mandatory in all patients.

  • Mitigate risk factors including hypertension, diabetes, hyperlipidemia.

  • Medical management (aspirin, statin, ± cilostazol) is in...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Postoperative open repair (6)

    • Monitor for surgical site hematoma (bleeding is highest risk, 4–17%).

    • Postoperative cardiac events occur in <5%...

REFERENCES

1
Setacci C, Galzerano G, Setacci F, et al. Endovascular approach to Leriche syndrome. J Cardiovasc Surg (Torino).  2012;53(3):301–306. [View Abstract on OvidMedline]
2
Al-Qaisi M, Nott D...

ADDITIONAL READING

  • Arnold JR, Greenberg J, Reddy K, et al. Internal mammary artery perfusing Leriche’s syndrome in association with significant coronary arteriosclerosis: four case reports and review ...

CODES

ICD10

I74.09 Other arterial embolism and thrombosis of abdominal aorta 

ICD9

444.09 Other arterial embolism and thrombosis of abdominal aorta 

SNOMED

307816004 Leriche’s syndrome (disorder) 

CLINICAL PEARLS

  • Reducing risk factors such as cigarette smoking, hypertension, and hypercholesterolemia is key to prevention.

  • Mainstay treatment involves medical management, endovascular or open repair...

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