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Leriche Syndrome

Melissa Jefferis, FAAFP, MD Reviewed 05/2023
 


BASICS

DESCRIPTION

  • Leriche syndrome, also known as aortoiliac occlusive disease, is characterized by a constellation of symptoms caused by atherosclerotic stenosis of the abdominal aorta as it bifurcat...

DIAGNOSIS

HISTORY

  • Male: erectile or ejaculatory dysfunction (2)

  • Intermittent claudication symptoms: cramping or atypical pain in thighs, hips, and buttocks exacerbated by walking and relieved with rest

  • ...

TREATMENT

GENERAL MEASURES

  • Encourage all patients who use tobacco products to quit.

  • Mitigate risk factors including hypertension, diabetes, hyperlipidemia.

  • Medical management (aspirin, statin, exercise, ...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Postoperative open repair

    • Monitor for surgical site hematoma (bleeding is highest risk, 4–17%).

    • Postoperative cardiac events occur in <5% of pa...

REFERENCES

1
Wooten C, Hayat M, du Plessis M, et al. Anatomical significance in aortoiliac occlusive disease. Clin Anat.  2014;27(8):1264-74.
2
Setacci  C, Galzerano  G, Setacci  F...

ADDITIONAL READING

  • Arnold  JR, Greenberg  J, Reddy  K, et al. Internal mammary artery perfusing Leriche’s syndrome in association with significant coronary arteriosclerosis:...

CODES

ICD10

I74.09 Other arterial embolism and thrombosis of abdominal aorta 

SNOMED

307816004 Leriche’s syndrome (disorder) 

CLINICAL PEARLS

  • Reducing risk factors such as cigarette smoking, hypertension, and hypercholesterolemia is key to prevention.

  • Mainstay treatment involves medical management, endovascular or open repair...

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