Acute lymphoblastic leukemia (ALL) in adults is the result of a clonal proliferation, survival, and impaired differentiation of immature lymphocytes. These early lymphoid cells take ...
Symptoms arise from sequelae of bone marrow suppression and/or from leukemic cell organ infiltration.
B symptoms: fever, weight loss, night sweats
Anemia: fatigue, shortness of breath, ...
Treatment of ALL determined by patient's age and presence of Philadelphia chromosome
Three phases to CTX, given with CNS prophylaxis at intervals throughout therapy:
Induction,...
Inpatient admission during induction CTX for continuous infusion and monitoring of complications
Weekly clinic visits with remission consolidatio...
Davis AS, Viera AJ, Mead MD. Leukemia: an overview for primary care. Am Fam Physician. 2014;89(9):731-8.
Puckett Y, Chan O. Acute Lymphocytic Leukemia...
C91.00 Acute lymphoblastic leukemia not having achieved remission
C91.01 Acute lymphoblastic leukemia, in remission
C91.02 Acute lymphoblastic leukemia, in relapse
91857003 Acute lymphoi...
ALL diagnosis is based on the presence of lymphoblasts or characteristic mutations in the bone marrow.
Hyper-CVAD is the main therapy.
Treatment at an appropriate cancer center for tailo...
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<bold>FIGURE 20-54. Acute lymphoblastic leukemia.</bold> The lymphoblasts in peripheral blood contain irregular and indented nuclei with prominent nucleoli and a moderate amount of cytoplasm.
<bold>FIGURE 20-54. Acute lymphoblastic leukemia.</bold> The lymphoblasts in peripheral blood contain irregular and indented n...
Acute lymphoblastic leukemia (L2 ALL). The lymphoblasts in the peripheral blood contain irregular and indented nuclei with prominent nucleoli and a moderate amount of cytoplasm.
Acute lymphoblastic leukemia (L2 ALL). The lymphoblasts in the peripheral blood contain irregular and indented nuclei with prominent nucle...