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Lung, Primary Malignancies

Abdel-Rahman Zakieh, MD, BS, MD, Arvey Stone and Phillip Knouse, M.D. Reviewed 06/2022
 


BASICS

DESCRIPTION

  • Primary lung cancers are the leading cause of cancer-related deaths in the United States (estimated 154,050 deaths in 2018, 25.3% of all cancer-related deaths).

  • Divided into two broad...

DIAGNOSIS

HISTORY

  • May be asymptomatic for most of course

  • Respiratory

    • Cough (new or change in chronic cough)

    • Wheezing and stridor

    • Dyspnea

    • Hemoptysis

    • Pneumonitis (fever and productive cough)

  • Constitutional

    • Malai...

TREATMENT

GENERAL MEASURES

  • NSCLC

    • Stage I, stage II, and selected stage III tumors are surgically resectable. Neoadjuvant or adjuvant therapy is recommended for select patients with high risk IB, II, and...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Depends on clinical history; in general, postoperative visits every 3 to 6 months in the first 2 years after surgery with physical exam and CT s...

REFERENCES

1
Aberle  DR, Adams  AM, Berg  CD, et al; and National Lung Screening Trial Research Team. Reduced lung-cancer mortality with low-dose computed tomographic screening....

ADDITIONAL READING

SEE ALSO

CODES

ICD10

  • C34.90 Malignant neoplasm of unsp part of unsp bronchus or lung

  • C34.10 Malignant neoplasm of upper lobe, unsp bronchus or lung

  • C34.30 Malignant neoplasm of lower lobe, unsp bronchus or lung

  • C3...

CLINICAL PEARLS

  • Two types: NSCLC and SCLC

    • NSCLC (>85% of all lung cancers); normally originate in periphery

      • Adenocarcinoma (~40% of NSCLC)

      • SCC (~25% of NSCLC)

      • Large cell (~10% of NSCLC)

    • SCLC centrally l...

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