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Lung, Primary Malignancies

Zeeshan Mirza, MD and Mohammad Razaq, MD Reviewed 06/2019
 


BASICS

DESCRIPTION

  • Primary lung cancers are the leading cause of cancer-related deaths in the United States (estimated 154,050 deaths in 2018, 25.3% of all cancer-related deaths).

  • Divided into two broad...

DIAGNOSIS

HISTORY

  • May be asymptomatic for most of course

  • Respiratory

    • Cough (new or change in chronic cough)

    • Wheezing and stridor

    • Dyspnea

    • Hemoptysis

    • Pneumonitis (fever and productive cough)

  • Constitutional

    • Malai...

TREATMENT

GENERAL MEASURES

  • NSCLC

    • Stage I, stage II, and selected stage III tumors are surgically resectable. Neoadjuvant or adjuvant therapy is recommended for many patients with high risk IB, II, and I...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Depends on clinical history; in general, postoperative visits every 3 to 6 months in the first 2 years after surgery with physical exam and CT s...

REFERENCES

1
Aberle DR, Adams AM, Berg CD, et al; and National Lung Screening Trial Research Team. Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med.  2011;3...

ADDITIONAL READING

National Cancer Institute. Lung cancer—health professional version https://www.cancer.gov/types/lung/hp. Accessed September 29, 2018. https://www.cancer.gov/types/lung/hp. Accessed ...

CODES

ICD10

  • C34.90 Malignant neoplasm of unsp part of unsp bronchus or lung

  • C34.10 Malignant neoplasm of upper lobe, unsp bronchus or lung

  • C34.30 Malignant neoplasm of lower lobe, unsp bronchus or lung

  • C3...

CLINICAL PEARLS

  • Two types: NSCLC and SCLC

    • NSCLC (>85% of all lung cancers); normally originate in periphery

      • Adenocarcinoma (~40% of NSCLC)

      • SCC (~25% of NSCLC)

      • Large cell (~10% of NSCLC)

    • SCLC centrally l...

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