Systemic lupus erythematosus (SLE) is a multisystem autoimmune inflammatory disease characterized by a chronic relapsing/remitting course; can be mild to severe and may be life-threa...
Fever, fatigue, malaise, weight loss, headache
Rash (discoid [LR+] = 18, malar [LR+] = 14), pho...
Education, counseling, and support
Influenza/pneumococcal vaccines are safe; weigh risk versus benefit for live vaccines in immunocompromised patients.
Low-estrogen oral contra...
Clinical evaluation for signs and symptoms
Weekly to monthly for active disease
Every 3 to 6 months for mild/inactive disease
Measures of disease a...
Lam NC, Ghetu MV, Bieniek ML. Systemic lupus erythematosus: primary care approach to diagnosis and management. Am Fam Physician. 2016;94(4):284–294. [View Abstract on OvidMedl...
M32.9 Systemic lupus erythematosus, unspecified
M32.10 Systemic lupus erythematosus, organ or system involv unsp
M32.14 Glomerular disease in systemic lupus erythematosus
M32.19 Oth organ or s...
Aggressiveness of therapy should reflect intensity of disease.
Most important diagnostic test is the UA: if abnormal, order kidney biopsy; serum and urine lab values often do not reveal...
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