The renal manifestation of systemic lupus erythematosus (SLE)
American College of Rheumatology (ACR) criteria: persistent proteinuria >500 mg/day or ≥3 on dipstick and/or presence ...
Assess for risk factors and other signs/symptoms of SLE: rash, photosensitivity, arthritis, neurologic complaints, fever, weight loss, alopecia.
Active nephritis is often accompanied b...
Monitor bone density; optimize vitamin D and calcium intake in p...
Monitor urine protein-to-creatinine ratio, urine microscopy, serum albumin and creatinine, antibody titers (especially anti-dsDNA), C3, C4, BP a...
Almaani S, Meara A, Rovin BH. Update on lupus nephritis. Clin J Am Soc Nephrol. 2017;12(5):825–835.
Kidney Disease: Improving Global Outcomes (KDIGO) Glomerulonephritis Work Gr...
710.0 Systemic lupus erythematosus
583.81 Nephritis and nephropathy, not specified as acute or chronic, in diseases classified e...
Early diagnosis, correct classification (requires renal biopsy), and rapid treatment improve renal survival in patients with LN.
Treat proliferative/progressive LN with a short inductio...
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